You discover a new species of poison-dart frog which secretes a neurotoxin in the skin mucous with LD50 of 0.5 mg/kg in humans. The toxin causes numbness, paralysis, arrhythmias, cardiac failure, and death. Based on the patch-clamp record of inward currents when the neurotoxin was applied to squid axon shown in Figure 2, suggest the mechanism of action of the neurotoxin. 500 PA 5 ms Figure 2 (Source: Google image)
You discover a new species of poison-dart frog which secretes a neurotoxin in the skin mucous with LD50 of 0.5 mg/kg in humans. The toxin causes numbness, paralysis, arrhythmias, cardiac failure, and death. Based on the patch-clamp record of inward currents when the neurotoxin was applied to squid axon shown in Figure 2, suggest the mechanism of action of the neurotoxin. 500 PA 5 ms Figure 2 (Source: Google image)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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![You discover a new species of poison-dart frog which secretes a neurotoxin in the skin mucous
with LD50 of 0.5 mg/kg in humans. The toxin causes numbness, paralysis, arrhythmias, cardiac
failure, and death. Based on the patch-clamp record of inward currents when the neurotoxin was
applied to squid axon shown in Figure 2, suggest the mechanism of action of the neurotoxin.
500 PA
5 ms
Figure 2 (Source: Google image)](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fd52bde2a-70f6-40a4-a920-1162983d2621%2F7b79b010-1913-43d7-9ee9-f5c000b22036%2Fkl7g6g7_processed.png&w=3840&q=75)
Transcribed Image Text:You discover a new species of poison-dart frog which secretes a neurotoxin in the skin mucous
with LD50 of 0.5 mg/kg in humans. The toxin causes numbness, paralysis, arrhythmias, cardiac
failure, and death. Based on the patch-clamp record of inward currents when the neurotoxin was
applied to squid axon shown in Figure 2, suggest the mechanism of action of the neurotoxin.
500 PA
5 ms
Figure 2 (Source: Google image)
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