You are working in the lab, with a cell-free translational system that contains microsomes. Microsomes are artificial structures derived from pieces of endoplasmic reticulum (ER) formed during tissue homogenization. These microsomes lack the signal recognition particle or SRP. You translate an mRNA that codes for a secretory protein using this system. Which of the following outcomes do you expect? The protein will be synthesized and its signal sequence will be removed O The protein will be synthesized and will be incorporated into the microsome O No protein synthesis O The protein will be synthesized and will not be incorporated into the microsome

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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You are working in the lab, with a cell-free translational system that contains
microsomes. Microsomes are artificial structures derived from pieces of endoplasmic
reticulum (ER) formed during tissue homogenization.
These microsomes lack the signal recognition particle or SRP.
You translate an mRNA that codes for a secretory protein using this system.
Which of the following outcomes do you expect?
The protein will be synthesized and its signal sequence will be removed
The protein will be synthesized and will be incorporated into the microsome
O No protein synthesis
The protein will be synthesized and will not be incorporated into the microsome
Transcribed Image Text:You are working in the lab, with a cell-free translational system that contains microsomes. Microsomes are artificial structures derived from pieces of endoplasmic reticulum (ER) formed during tissue homogenization. These microsomes lack the signal recognition particle or SRP. You translate an mRNA that codes for a secretory protein using this system. Which of the following outcomes do you expect? The protein will be synthesized and its signal sequence will be removed The protein will be synthesized and will be incorporated into the microsome O No protein synthesis The protein will be synthesized and will not be incorporated into the microsome
Expert Solution
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The production of protein from the mRNA sequence is known as translation process which is performed by the ribosomes. Within the cell two types of ribosomes are found that are- membrane free ribosome and membrane bound ribosome (bounded on the membrane of endoplasmic reticulum).

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