You are studying a new inhibitor that you know preventsproper formation of ribosomes by binding to, andinhibiting, one of the eukaryotic RNA polymerases.Which polymerase(s) could it potentially be binding to andwhy would that prevent proper ribosome formation?

Let's break down the explanation further and provide an example to illustrate the concept: RNA…

Answered: You are studying a new inhibitor that…

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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Similar questions

1. why is the ribosome a good drug target? 2. Tetracyclines: a. Where do first generation tetracyclines bind? b. Which step in protein translation do they inhibit? C. Why was it necessary to come out with a third generation tetracycline, and how are they different? 3. What are three ways that 2-deoxystreptamine (2-DOS) aminoglycosides can inhibit protein synthesis? 4. Chloramphenicol: a. Where does this drug bind? b. How does it inhibit protein synthesis?
You plan to synthesize a peptide to be used as a vaccine to treat melanoma, a particularly aggressive form of skin cancer. Normally, gp100, a protein on the surface of melanocytes, activates cell growth when it is bound by its ligand. Activation of the growth pathway depends on the presence of threonine in the ligand. The effective peptide vaccine will mimic the natural ligand, but won’t cause cell growth and division. Below is the sequence of the natural ligand: LDMKTAG In order to ensure your newly designed peptide vaccine does not cause cell growth upon binding, you must substitute the Threonine residue at position 5. What amino acid would you replace it with, bearing in mind that the peptide should still be similar enough to bind to the gp100 protein in the surface of melanocytes. Explain your choice. Your vaccine will be administered as a topical cream, and you require your peptide to have an overall neutral charge in order to be functional. At what pH should you formulate…
RNA polymerase in Escherichia coli normally synthesizes all of the following molecules except: RNA primers during DNA replication messenger RNA (mRNA) transfer RNA (tRNA) ribosomal RNA (rRNA) heterogenous nuclear RNA (hnRNA)
In what way is ribozymal activity essential to modem life, based on our coverage? It catalyzes folding of each tRNA. It catalyzes pyrophosphate hydrolysis. It catalyzes peptide bond formation. It catalyzes hydrolysis of the fully-translated polypeptide from the final RNA. It catalyzes charging of each tRNA.
All of the following regarding ribosomes are true EXCEPT: A. Ribosomes are comprised of protein and RNA. B. Ribosomes coordinate with initiation and elongation factors to regulate translation. C. Ribosomes bind transcripts in their promoters. D. Prokaryotic ribosomes are comprised of a large and a small subunit. E. Ribosomes in eukaryotic cells bind to complete transcripts.
The structure of a prodrug used for treating people with HIV virus (human immunodeficiency virus) and AIDS is shown below. This molecule is a precursor of a protease inhibitor that competitively inhibits HIV protease due to its resemblance to the proteolytic site of the enzyme. Which process in the viral life cycle does this inhibitor target directly ? Group of answer choices a. viral protein processing for making new viruses b. viral mRNA synthesis c. viral DNA integration into the host cell DNA d. viral DNA synthesis
One remarkable feature of the genetic code is that amino acids with similar chemical properties often have similar codons. thus codons with U or C as the second nucleotide tend to specify hydrophobic amino acids. Can you suggest a possible explanation for this phenomenon in terms of the early evolution of the protein-synthesis machinery?
Transcription and translation can occur simultaneously in the cytoplasm of a prokaryote. O 1) True O 2) False
Order the following choices to indicate the sequence of steps in the process of elongation of a growing peptide chain. Peptidyltransferase reaction catalyzed by large rRNA subunit. Aminoacyl-tRNA binds the ribosomal A site via EF1x-GTP hydrolysis. EF2-GTP hydrolysis promotes translocation of the ribosome. Release of EF1«-GDP. >
Put the following steps of transcription in order

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You are studying a new inhibitor that you know prevents proper formation of ribosomes by binding to, and inhibiting, one of the eukaryotic RNA polymerases. Which polymerase(s) could it potentially be binding to and why would that prevent proper ribosome formation?