You are studying a gene that controls ossicone (horn) length in giraffes. The wild type long-ossicone allele (L) is dominant to the mutant short-ossicone (I) allele. However the L allele is only 60% penetrant. You cross a long-horn heterozygous giraffe to a short- horn giraffe. What phenotypic progeny classes do you expect and at what frequencies?
You are studying a gene that controls ossicone (horn) length in giraffes. The wild type long-ossicone allele (L) is dominant to the mutant short-ossicone (I) allele. However the L allele is only 60% penetrant. You cross a long-horn heterozygous giraffe to a short- horn giraffe. What phenotypic progeny classes do you expect and at what frequencies?
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
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![### Studying Ossicone Length in Giraffes
In this educational module, we will explore the genetic basis of ossicone (horn) length in giraffes. Specifically, we will examine the inheritance pattern of a gene that controls this trait.
#### Background Information
The gene in question has two alleles:
- **L**: The wild type allele, which results in long ossicones.
- **l**: The mutant allele, which results in short ossicones.
The wild type allele (**L**) is dominant over the mutant short-ossicone allele (**l**). However, the **L** allele exhibits incomplete penetrance, with only 60% of the individuals who carry the allele expressing the long ossicone phenotype.
#### Genetic Cross
Consider a genetic cross between a long-horn heterozygous giraffe (**Ll**) and a short-horn giraffe (**ll**).
#### Predicting Phenotypic Progeny and Their Frequencies
Using a Punnett square, we predict the genotypic ratio:
| Parent Genotype | ll | Ll |
|-----------------|------|------|
| Phenotype | Short| Long |
| Frequency | 50% | 50% |
Given the penetrance of the **L** allele (60%), the phenotypic ratio among the offspring is adjusted as follows:
1. **Ll genotype (50% of offspring)**:
- 60% show long ossicones = 0.60 * 0.50 = 30%
- 40% show short ossicones = 0.40 * 0.50 = 20%
2. **ll genotype (50% of offspring)**:
- 100% show short ossicones = 50%
Summing up the probabilities:
- **Long-ossicone giraffes**: 30%
- **Short-ossicone giraffes**: 20% (from **Ll**) + 50% (from **ll**), totaling 70%
Therefore, the phenotypic progeny classes expected and their frequencies are:
- **Long-ossicone giraffes**: 30%
- **Short-ossicone giraffes**: 70%](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F2a42a7f4-7147-4407-ae0e-5b84a734bd0d%2Fe0d3acd0-77da-4ac3-9de9-e3544ab62d93%2Fj4uok0q.jpeg&w=3840&q=75)
Transcribed Image Text:### Studying Ossicone Length in Giraffes
In this educational module, we will explore the genetic basis of ossicone (horn) length in giraffes. Specifically, we will examine the inheritance pattern of a gene that controls this trait.
#### Background Information
The gene in question has two alleles:
- **L**: The wild type allele, which results in long ossicones.
- **l**: The mutant allele, which results in short ossicones.
The wild type allele (**L**) is dominant over the mutant short-ossicone allele (**l**). However, the **L** allele exhibits incomplete penetrance, with only 60% of the individuals who carry the allele expressing the long ossicone phenotype.
#### Genetic Cross
Consider a genetic cross between a long-horn heterozygous giraffe (**Ll**) and a short-horn giraffe (**ll**).
#### Predicting Phenotypic Progeny and Their Frequencies
Using a Punnett square, we predict the genotypic ratio:
| Parent Genotype | ll | Ll |
|-----------------|------|------|
| Phenotype | Short| Long |
| Frequency | 50% | 50% |
Given the penetrance of the **L** allele (60%), the phenotypic ratio among the offspring is adjusted as follows:
1. **Ll genotype (50% of offspring)**:
- 60% show long ossicones = 0.60 * 0.50 = 30%
- 40% show short ossicones = 0.40 * 0.50 = 20%
2. **ll genotype (50% of offspring)**:
- 100% show short ossicones = 50%
Summing up the probabilities:
- **Long-ossicone giraffes**: 30%
- **Short-ossicone giraffes**: 20% (from **Ll**) + 50% (from **ll**), totaling 70%
Therefore, the phenotypic progeny classes expected and their frequencies are:
- **Long-ossicone giraffes**: 30%
- **Short-ossicone giraffes**: 70%
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