You are studying a gene that controls ossicone (horn) length in giraffes. The wild type long-ossicone allele (L) is dominant to the mutant short-ossicone (I) allele. However the L allele is only 60% penetrant. You cross a long-horn heterozygous giraffe to a short- horn giraffe. What phenotypic progeny classes do you expect and at what frequencies?

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### Studying Ossicone Length in Giraffes

In this educational module, we will explore the genetic basis of ossicone (horn) length in giraffes. Specifically, we will examine the inheritance pattern of a gene that controls this trait.

#### Background Information
The gene in question has two alleles:
- **L**: The wild type allele, which results in long ossicones.
- **l**: The mutant allele, which results in short ossicones.

The wild type allele (**L**) is dominant over the mutant short-ossicone allele (**l**). However, the **L** allele exhibits incomplete penetrance, with only 60% of the individuals who carry the allele expressing the long ossicone phenotype.

#### Genetic Cross
Consider a genetic cross between a long-horn heterozygous giraffe (**Ll**) and a short-horn giraffe (**ll**). 

#### Predicting Phenotypic Progeny and Their Frequencies
Using a Punnett square, we predict the genotypic ratio:

| Parent Genotype | ll   | Ll   |
|-----------------|------|------|
| Phenotype       | Short| Long |
| Frequency       | 50%  | 50%  |

Given the penetrance of the **L** allele (60%), the phenotypic ratio among the offspring is adjusted as follows:

1. **Ll genotype (50% of offspring)**:
   - 60% show long ossicones = 0.60 * 0.50 = 30%
   - 40% show short ossicones = 0.40 * 0.50 = 20%

2. **ll genotype (50% of offspring)**:
   - 100% show short ossicones = 50%

Summing up the probabilities:
- **Long-ossicone giraffes**: 30%
- **Short-ossicone giraffes**: 20% (from **Ll**) + 50% (from **ll**), totaling 70%

Therefore, the phenotypic progeny classes expected and their frequencies are:
- **Long-ossicone giraffes**: 30%
- **Short-ossicone giraffes**: 70%
Transcribed Image Text:### Studying Ossicone Length in Giraffes In this educational module, we will explore the genetic basis of ossicone (horn) length in giraffes. Specifically, we will examine the inheritance pattern of a gene that controls this trait. #### Background Information The gene in question has two alleles: - **L**: The wild type allele, which results in long ossicones. - **l**: The mutant allele, which results in short ossicones. The wild type allele (**L**) is dominant over the mutant short-ossicone allele (**l**). However, the **L** allele exhibits incomplete penetrance, with only 60% of the individuals who carry the allele expressing the long ossicone phenotype. #### Genetic Cross Consider a genetic cross between a long-horn heterozygous giraffe (**Ll**) and a short-horn giraffe (**ll**). #### Predicting Phenotypic Progeny and Their Frequencies Using a Punnett square, we predict the genotypic ratio: | Parent Genotype | ll | Ll | |-----------------|------|------| | Phenotype | Short| Long | | Frequency | 50% | 50% | Given the penetrance of the **L** allele (60%), the phenotypic ratio among the offspring is adjusted as follows: 1. **Ll genotype (50% of offspring)**: - 60% show long ossicones = 0.60 * 0.50 = 30% - 40% show short ossicones = 0.40 * 0.50 = 20% 2. **ll genotype (50% of offspring)**: - 100% show short ossicones = 50% Summing up the probabilities: - **Long-ossicone giraffes**: 30% - **Short-ossicone giraffes**: 20% (from **Ll**) + 50% (from **ll**), totaling 70% Therefore, the phenotypic progeny classes expected and their frequencies are: - **Long-ossicone giraffes**: 30% - **Short-ossicone giraffes**: 70%
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