Women with urinary tract infections caused by E. coli are generally treated with a course of antibiotics. A common complication of the antibiotic treatment is the occurrence of a vaginal yeast infection caused by Candida albicans, an organism that is normally present in very low numbers in the human vaginal tract. This complication occurs because: The E. coli infection damages the reproductive epithelium, causing a breach in the tight junctions and allowing invasion by the Candida albicans. The E. coli infection induces adhesion molecule expression on the reproductive epithelium, allowing attachment of the yeast. The antibiotic treatment kills all strains of fungi present in the reproductive tract, except the Candida albicans. The E. coli infection causes gastrointestinal distress leading to diarrhea. The antibiotics kill many of the commensal organisms in the reproductive tract, allowing overgrowth of the fungus.

Phlebotomy Essentials
6th Edition
ISBN:9781451194524
Author:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Publisher:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Chapter1: Phlebotomy: Past And Present And The Healthcare Setting
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Women with urinary tract infections caused by E. coli are generally treated with a course of antibiotics. A common complication of the antibiotic treatment is the occurrence of a vaginal yeast infection caused by Candida albicans, an organism that is normally present in very low numbers in the human vaginal tract. This complication occurs because:

  1. The E. coli infection damages the reproductive epithelium, causing a breach in the tight junctions and allowing invasion by the Candida albicans.
  2. The E. coli infection induces adhesion molecule expression on the reproductive epithelium, allowing attachment of the yeast.
  3. The antibiotic treatment kills all strains of fungi present in the reproductive tract, except the Candida albicans.
  4. The E. coli infection causes gastrointestinal distress leading to diarrhea.
  5. The antibiotics kill many of the commensal organisms in the reproductive tract, allowing overgrowth of the fungus.
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