With directional selection against the A₁ allele we can predict that it will either become rare or go extinct (frequency = 0). Which result occurs depends on the dominance relationships of the alleles. In which situation would the A₁ allele be LEAST likely to go extinct? Think about what kind of dominance exists in a lot of disease- causing alleles. The A, allele is dominant to the A, allele. The alleles are incompletely dominant (or co-dominant). The A, allele is dominant to the A, allele.
Genetic Variation
Genetic variation refers to the variation in the genome sequences between individual organisms of a species. Individual differences or population differences can both be referred to as genetic variations. It is primarily caused by mutation, but other factors such as genetic drift and sexual reproduction also play a major role.
Quantitative Genetics
Quantitative genetics is the part of genetics that deals with the continuous trait, where the expression of various genes influences the phenotypes. Thus genes are expressed together to produce a trait with continuous variability. This is unlike the classical traits or qualitative traits, where each trait is controlled by the expression of a single or very few genes to produce a discontinuous variation.
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