Why is the RNA polymerase/RNA/DNA duplex of the RNA polymerizing complex called transcription bubble? What is the local change in Lk, Tw and Wr within the RNA polymerase DNA  transcription bubble?

Q: Although initiation requires the sigma factor or sigma subunit be associated with the core RNA…

A: Transcription is a process by which RNA is synthesized using DNA as template. Transcription occurs…

Q: What is a disorder caused by errors in transcription? What kind of error is involved?

A: Transcription is defined as the process by which the information present in a DNA strand is copied…

Q: Consider the Rho-dependent terminator sequence 5’CCCAGCCCGCCUAAUGAGCGGCCUUUUUUUU-3’. What affect…

A: The mutation is the change in the nucleotide sequence of the DNA. The point mutation is the mutation…

Q: Which is the transcription is catalysed by RNA polymerase?

A: Transcription is a process in which DNA sequence of a gene is copied into RNA and for this DNA helix…

Q: bacterial RNA polymerase

A: Introduction : The DNA-dependent multisubunit RNA polymerase (RNAP) of bacteria is the most…

Q: What kind of protein required for the initiation of transcription by RNApolymerase ?

A: Introduction  Transcription: it is the formation of transcript or RNA, which can be coding or…

Q: How does an activator protein help RNA polymerasebegin transcription?

A: Transcription is a process in which the nucleotide sequences of a gene are transcribed into the mRNA…

Q: How does the intrinsically disordered C-terminal domain of RNA polymerase II contribute to the…

A: C terminal  domain of RNA polymerase II consists of a block of seven amino acids with the consensus…

Q: What are the roles of sigma factor, rho factor, and an intrinsic terminator in transcription in…

A: Introduction: Transcription is the synthesis of single-stranded messenger RNA (mRNA) from the…

Q: Select whether each of the components are associated with eukaryotic or prokaryotic transcription.…

A: The expression of the genetic material occurs generally through the production of proteins. This…

Q: What is the function of LARP1 and where does it bind? Select an answer and submit. For keyboard…

A: Translation is the process by which ribosomes in the cytoplasm or endoplasmic reticulum make…

Q: Why is TBP considered to be a universal transcription factor?

A: The TATA-binding protein is a general transcription factor that binds specifically to a DNA sequence…

Q: The CTD of the largest subunit of RNA polymerase II can be phosphorylated at multiple serine…

A: RNA (ribonucleic acid) polymerase II is the holoenzyme found in eukaryotes which promotes the gene…

Q: Initiation of transcription in prokaryotic cells requires not only RNA polymerase, but also an…

A: The sites of transcription on the DNA has three main regions viz., promoter region (upstream of the…

Q: So I know that most DNA viruses use the cell’s DNA-dependent RNA polymerases to make mRNAs for…

A: cap snatching is a process during transcription initiation that reduces the size of the nucleotide…

Q: What would be the likely effect of a mutation that prevents s from dissociating from the RNA…

A: RNA polymerase or DNA dependent RNA polymerase is an enzyme that synthesizes RNA from the template…

Q: During eukaryote transcription initiation, when TFIIE, TFIIA, TFIIB, TFIIF, and RNA pol II all join…

A: Transcription factor is a protein that binds to a specific region in DNA that controls the…

Q: What are the similarities and differences in the initiation of gene transcription in bacteria and…

A: similarities and differences in the initiation of gene transcription in bacteria and eukaryotes

Q: Explain Classes of RNA Transcribed by the Three Eukaryotic Nuclear RNA Polymerases and Their…

A: Transcription Cellular process in which RNA is synthesized using DNA as a template known as…

Q: Which RNA conformation favors transcription—the form with the antiterminator stem-loop or the form…

A: The process of transcription allows the formation of RNA from DNA with help of DNA-dependent RNA…

Q: Which of the following is/are true regarding transcription initiation in bacteria? I. TFIID will…

A: To start transcribing a gene, RNA polymerase binds to the promoter region of the gene's DNA.... The…

Q: Please match the gene element with the the correct definition. control elements 5' UTR 3' UTR…

A: The process by which genetic information encoded in DNA is copied into RNA is known as…

Q: What is the composition of minimal initiation complex during transcription? TBP, TAF, TFIIA, TFIIB,…

A: In eukaryotes several transcription factors are necessary for the basal expression of an eukaryotic…

Q: What would be the likely effect of a mutation that prevents σ from dissociating from the RNA…

A: After the initiation of the transcription, the RNA strand would elongate by the action of RNA…

Q: Explain about Formation of the RNA Polymerase II Transcription Initiation Complex ?

A: The process of transcription (synthesis of RNA from DNA) is initiated when RNA polymerase binds to…

Q: What is the function of the sigma subunit in RNA polymerase?

A: RNA polymerase is the chief enzyme, which is involved in copying the coded genetic information from…

Q: what is the role of rna polymerase? Does it catalyzes the polymerization step (adding new nucleotide…

A: RNA polymerase is a critical enzyme in the transcription process, which is the first step in gene…

Q: What structural change occurs in the DNA when an “open” transcription initiation complex is formed?

A: When an “open” transcription initiation complex is formed then this leads to the…

Q: When an activator protein interacts with mediator, how does this affect the function of RNA…

A: RNA polymerase is an enzyme that is responsible for copying a DNA sequence into an RNA sequence,…

Q: Where in the many steps of transcription initiation does regulation occur?

A: Transcriptional regulation: It can be defined as a mechanism that collectively helps in regulating…

Q: 7) Which of the following needs to occur for transcription to take place in prokaryotes? A) The RNA…

A: Prokaryotic transcription is the process by which the genetic material in prokaryotes is converted…

Q: Where in a eukaryotic cell does the molecular product of transcription (Eukaryotic Transcription) go…

A: In a eukaryotic cell, transcription occurs in the nucleus, and translation occurs at ribosomes in…

Q: Once an RNA polymerase has initiated transcription, it will release the sigma factor or sigma…

A: TRANSCRIPTION- The process of formation of mRNA from the DNA strand is known as transcription. It is…

Q: Name the factor of RNA polymerase enzymes which recoganise the start and termination signal on DNA…

A: All transcription in bacteria is performed by the single type of RNA polymerase.  This polymerase…

Q: Why is an NFR needed at the core promoter for transcription to occur?

A: DNA is the genetic material in most living organisms. It is the information hub of the cell that…

Q: in the CTD of RNA polymerase II is phosphorylated to recruit enzymes to add the 5’ guanosine cap?…

A: During the being transcription cycle, the C-terminal domain (CTD) of the most important part of RNA…

Q: Once an RNA polymerase has initiated transcription, it will release the sigma factor or sigma…

A: RNA polymerase is a multi-unit enzyme that uses transcription to create RNA molecules from a DNA…

Q: Which step in elongation is catalyzed by RNA polymerase?

A: RNA polymerase is an enzyme responsible for catalyzing the process of transcription, which is the…

Gene Interactions

When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.

Gene Expression

Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.