What are the roles of sigma factor, rho factor, and an intrinsic terminator in transcription in prokaryotes?

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
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What are the roles of sigma factor, rho factor, and an intrinsic terminator in transcription in prokaryotes?

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Introduction:

Transcription is the synthesis of single-stranded messenger RNA (mRNA) from the double-stranded DNA base and the enzyme RNA polymerase is required for this reaction to occur. The process involves three important steps:

a. Initiation: The enzyme RNA polymerase attaches to the DNA region which is called the promoter and the synthesis starts from here. 

b. Elongation: The RNA which is formed newly starts to grow.

c. Termination: The enzyme RNA polymerase reaches the terminator DNA and gets detached from the newly formed RNA transcript and the double-stranded DNA. 

 

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