Why do amino acids display a lower pK, value for the carboxylic acid group compared to acetic acid? The chirality of the amino acid favors the deprotonation of the carboxylic acid function. The ammonium function on the chiral center helps to stabilize the negative charge on the carboxylate. Amino acids have a higher melting point than acetic acid. The carboxylate ion is stabilized by the side chain of the amino acid. The negative charge on the carboxylate is stabilized by resonance with the amino group.
Why do amino acids display a lower pK, value for the carboxylic acid group compared to acetic acid? The chirality of the amino acid favors the deprotonation of the carboxylic acid function. The ammonium function on the chiral center helps to stabilize the negative charge on the carboxylate. Amino acids have a higher melting point than acetic acid. The carboxylate ion is stabilized by the side chain of the amino acid. The negative charge on the carboxylate is stabilized by resonance with the amino group.
Biochemistry
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ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
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