While working with Drosophila, you discover a mutant with green eyes. You first create a strain of flies that are pure-breeding for this mutation (but wild-type for everything else). You name the mutant gene grn and set out to discover which chromosome it is on and begin to map its location. In one experiment, you cross grn flies with min flies (miniature wings) to create flies that are hybrid for both traits (F1 flies). Then, you cross the F1 flies with each other to generate F2 flies. 1.) What chromosome is the gene called “miniature wings” on? (Use the genetic map from the textbook, also found in the PPT presentation for chapter 4.) 2.) What percentage of the F2 flies will be double-mutant (green eyes and miniature wings)? Next, you perform another experiment. This time, you first take the F2 double-mutant flies from the first cross and cross them with double wild-type flies to create a new batch of double-hybrids (F1). 3.) Give the genotypes of the P1 cross described above. 4.) Give the genotype(s) and phenotype(s) of the F1 progeny of this cross?

Human Anatomy & Physiology (11th Edition)
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ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
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While working with Drosophila, you discover a mutant with green eyes. You first create a strain of flies
that are pure-breeding for this mutation (but wild-type for everything else). You name the mutant gene
grn and set out to discover which chromosome it is on and begin to map its location. In one experiment,
you cross grn flies with min flies (miniature wings) to create flies that are hybrid for both traits (F1 flies).
Then, you cross the F1 flies with each other to generate F2 flies.
1.) What chromosome is the gene called “miniature wings” on? (Use the genetic map from the
textbook, also found in the PPT presentation for chapter 4.)
2.) What percentage of the F2 flies will be double-mutant (green eyes and miniature wings)?
Next, you perform another experiment. This time, you first take the F2 double-mutant flies from the first
cross and cross them with double wild-type flies to create a new batch of double-hybrids (F1).
3.) Give the genotypes of the P1 cross described above.
4.) Give the genotype(s) and phenotype(s) of the F1 progeny of this cross?
Then you perform a test cross to help determine if the grn and min genes are on the same chromosome.
5.) Give the genotypes and phenotypes of the parent flies in this testcross.

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