Gene A and B are 500,000 bp apart - the genes are either side of a recombination hot spot. Gene C and D are also 500,000 bp apart but the region containing genes C and D are not near a recombination hot spot. Would the map distance between A and B be the same as the map distance between C and D? Explain your answer.
Genetic Recombination
Recombination is crucial to this process because it allows genes to be reassorted into diverse combinations. Genetic recombination is the process of combining genetic components from two different origins into a single unit. In prokaryotes, genetic recombination takes place by the unilateral transfer of deoxyribonucleic acid. It includes transduction, transformation, and conjugation. The genetic exchange occurring between homologous deoxyribonucleic acid sequences (DNA) from two different sources is termed general recombination. For this to happen, an identical sequence of the two recombining molecules is required. The process of genetic exchange which occurs in eukaryotes during sexual reproduction such as meiosis is an example of this type of genetic recombination.
Microbial Genetics
Genes are the functional units of heredity. They transfer characteristic information from parents to the offspring.
* Recombination hot spots are the regions of genome where it can undergoes recombination in higher rates as compared to around.
* Thes recombination hotspots will help to get genomic diversity in the population.
* They are present in the multiple locations within genome.
* In humans these spots are absent.
*Many crossover would likely happen at this hotspot.
*A genetic map distance is not considered by looking physical distance.
*The probability of a crossover occurring along the distance between loci on a chromosome is the estimation of genetic map.
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