Which receptor induces glycogenolysis in skeletal muscle? Group of answer choices Tyrosine kinase cell surface receptor G-Protein alpha s cell surface receptor estrogen nuclear receptor PKC receptor
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- When nerve cells contact each other, they form adherens junctions (AJs) at the point of contact. The main transmembrane (TM) protein in the junctions is N-cadherin. N-cadherin is a single pass TM protein with a short intracellular domain and a large extracellular domain on the amino end. Proper formation of the AJs requires both actin (MF) and microtubules (MTs). Motor proteins for MTs are dynein (-) end and kinesin (+) end (and were discovered by Michael Sheetz). Maintenance of preformed AJs requires MFs . Adding drugs that disrupt MFs causes AJs to fall apart, and the N-cadherin is removed from the PM (by endocytosis). If the drugs are removed, MTs (& MFs) are required to restore the N-cadherin to the plasma membrane. choose answer for D1 and D2 D. Suppose cells contain a soluble kinase that modifies N-cadherin that has been removed from the PM. D-1. The kinase could catalyze modification(s) of the side chains of amino acids near (the N end) (the C end) (either end, but not…Please explain the mechanismPlease answer both, thank you
- Can you please explain me the following: regulation of receptors: homologous and heterologous receptor desensitization, receptor internalization and trafficking, receptor down-regulationxytocin stimulates contraction of smooth muscles in the breast and uterine wall. The key step in muscle contraction is release of calcium from internal cell stores. With which type of receptor does oxytocin interact to cause muscle contraction? A. Gαi-coupled receptor B. Tyrosine kinase coupled receptor C. Cytokine type 1 receptor D. Ser/Thr kinase receptor E. Gαq-coupled receptorWhich of the following will bind (directly or indirectly) to the phosphate groups on a tyrosine kinase receptor? Ras-GEF Ran-GEF Rab-GEF Sar-GEF O Raf-GEF
- BHK-21 are what type of cell? muscle fibroblast nerve epithelailChoose the item in column 2 that best matches each item in column 1. necessary for the activation of heterotrimeric G-proteins primary signal that activates platelets pertussis toxin adenylate cyclase hormones acting over long distances…Which of the following would inhibit the activity of TGF-Beta receptor? multiple answers A. Deletion of Extracellular domain B. Tyrosine Kinase Inhibitor C. Mutation that prevents homodimerization of Type II Receptor D. Mutation of phosphorylation site on Type I receptor E. Inhibition Type II receptor binding to Type I receptor
- Which of the following is a second messenger signal ? Camp Ip3 DAG G protein coupled receptor A, b and cSort the following items based on which stage they are involved in: reception, transduction or response. Signaling molecule Receptor lyrosine kinase Protein synthesis G protein-coupled receptor cAMP Second messenger Ca2+ Phosphorylation cascade IP3 Adenylyl cyclaseGive correct typing answer with explanation