Which of the following statements best defines the term ‘spare receptors’? ‘Spare receptors’ refers to receptors that are broken down by cells because they are surplus to requirements. ‘Spare receptors’ occur when the KD for agonist binding to the receptor is smaller than the EC50 determined for a particular physiological response. ‘Spare receptors’ refers to the pool of intracellular receptors that are able to translocate to the plasma membrane. ‘Spare receptors’ can be defined as the number of receptors not occupied by agonist when a maximal response has been achieved, compared to the total number of receptors in the cell.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
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Which of the following statements best defines the term ‘spare receptors’?

   

‘Spare receptors’ refers to receptors that are broken down by cells because they are surplus to requirements.

   

‘Spare receptors’ occur when the KD for agonist binding to the receptor is smaller than the EC50 determined for a particular physiological response.

   

‘Spare receptors’ refers to the pool of intracellular receptors that are able to translocate to the plasma membrane.

   

‘Spare receptors’ can be defined as the number of receptors not occupied by agonist when a maximal response has been achieved, compared to the total number of receptors in the cell.

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