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Which of the following questions would be most appropriate to investigate whether the proteolytic enzymes are evolutionarily conserved among species?

Which of the following questions would be most appropriate to investigate whether the proteolytic enzymes are evolutionarily conserved among species?

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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### Cell Signaling and Proteolytic Enzymes **Introduction:** Cells release active signaling proteins when membrane-bound precursor proteins are cleaved by proteolytic enzymes. These signaling proteins then bind to receptors on the surface of target cells, thereby activating an intracellular signaling pathway and eliciting a response from the target cell. **Activation Mechanism:** This mechanism of activating receptor-binding signaling proteins has been observed in a variety of organisms from bacteria to humans. Many of the enzymes responsible for the proteolysis of membrane-bound precursor proteins have been isolated and characterized. **Research Question:** Which of the following questions would be most appropriate to investigate whether the proteolytic enzymes are evolutionarily conserved among species? - Once the precursor proteins of different species are cleaved, do the active signaling proteins bind to the same receptors on different target cells? - If a proteolytic enzyme from one species is incubated with a precursor protein from another species, does correct cleavage occur? - Are the proteolytic enzymes synthesized in the rough endoplasmic reticulum of all species? - Are the genes encoding the proteolytic enzymes expressed in the same cell types in all species? **Explanation of Graphs and Diagrams:** There are no graphs or diagrams present in this image that require detailed explanation. By considering such questions, researchers can better understand the conservation and variation of proteolytic enzymes across different species, shedding light on evolutionary processes and functional similarities.
Transcribed Image Text:### Cell Signaling and Proteolytic Enzymes **Introduction:** Cells release active signaling proteins when membrane-bound precursor proteins are cleaved by proteolytic enzymes. These signaling proteins then bind to receptors on the surface of target cells, thereby activating an intracellular signaling pathway and eliciting a response from the target cell. **Activation Mechanism:** This mechanism of activating receptor-binding signaling proteins has been observed in a variety of organisms from bacteria to humans. Many of the enzymes responsible for the proteolysis of membrane-bound precursor proteins have been isolated and characterized. **Research Question:** Which of the following questions would be most appropriate to investigate whether the proteolytic enzymes are evolutionarily conserved among species? - Once the precursor proteins of different species are cleaved, do the active signaling proteins bind to the same receptors on different target cells? - If a proteolytic enzyme from one species is incubated with a precursor protein from another species, does correct cleavage occur? - Are the proteolytic enzymes synthesized in the rough endoplasmic reticulum of all species? - Are the genes encoding the proteolytic enzymes expressed in the same cell types in all species? **Explanation of Graphs and Diagrams:** There are no graphs or diagrams present in this image that require detailed explanation. By considering such questions, researchers can better understand the conservation and variation of proteolytic enzymes across different species, shedding light on evolutionary processes and functional similarities.
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