Which of the following combinations should not be used for treatment of hypertension in patients with erectile dysfunction?A. Dosartan + torasemideB. Lisinopril + furosemideC. Doxazosin + tadanafilD. Nimodipine + sildenafilE. Metoprolol + spironolactone

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Which of the following combinations should not be used for treatment of hypertension in patients with erectile dysfunction?
A. Dosartan + torasemide
B. Lisinopril + furosemide
C. Doxazosin + tadanafil
D. Nimodipine + sildenafil
E. Metoprolol + spironolactone

Expert Solution
Step 1:

An erection occurs when blood fills the penis. Normally, when a man becomes sexually aroused, blood vessels, muscles, nerves, and hormones work together to create an erection. Symptoms of ED can occur when this process is disrupted.

 

Potassium-sparing diuretics  directly or indirectly block aldosterone, a hormone that raises blood pressure by causing the kidneys to conserve sodium and water. As a result, spironolactone medications are sometimes also known as aldosterone-receptor blockers.  It also affect other hormones and thus causes severe unwanted side effects,such as erectile disfunction in men.

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