What is the total yield of NADH, FADH2, and acetyl-CoA from the complete oxidation of myristate?  Assuming all of these metabolites are oxidized by the citrate cycle and oxidative phosphorylation, what is the net yield of ATP?

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
icon
Related questions
icon
Concept explainers
Question

385

Fatty Oxidation and Ketogenesis

Q5.3:   What is the total yield of NADH, FADH2, and acetyl-CoA from the complete oxidation of myristate?  Assuming all of these metabolites are oxidized by the citrate cycle and oxidative phosphorylation, what is the net yield of ATP?

Expert Solution
Step 1

Myristic acid is a fatty acid with 14 carbon atoms.

Beta-oxidation is the oxidation of fatty acid on the beta-carbon atom, with the sequential removal of two carbon atoms in the form of acetyl CoA.

Three major steps involved in the beta-oxidation are:

  • Activation of fatty acid (in the cytosol)
  • Transport of fatty acid to the mitochondria.
  • Beta-oxidation in the mitochondrial matrix.

 

steps

Step by step

Solved in 2 steps

Blurred answer
Knowledge Booster
Metabolic pathways
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biochemistry and related others by exploring similar questions and additional content below.
Similar questions
Recommended textbooks for you
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781319114671
Author:
Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:
W. H. Freeman
Lehninger Principles of Biochemistry
Lehninger Principles of Biochemistry
Biochemistry
ISBN:
9781464126116
Author:
David L. Nelson, Michael M. Cox
Publisher:
W. H. Freeman
Fundamentals of Biochemistry: Life at the Molecul…
Fundamentals of Biochemistry: Life at the Molecul…
Biochemistry
ISBN:
9781118918401
Author:
Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher:
WILEY
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305961135
Author:
Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher:
Cengage Learning
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305577206
Author:
Reginald H. Garrett, Charles M. Grisham
Publisher:
Cengage Learning
Fundamentals of General, Organic, and Biological …
Fundamentals of General, Organic, and Biological …
Biochemistry
ISBN:
9780134015187
Author:
John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. Peterson
Publisher:
PEARSON