What is the most likely diagnosis? And why? Use the bone marrow biopsy and the CBC results included to justify the answer. -Justify the diagnosis using the morphology of the cells listed in CBC section. Compare it with the reference ranges.
What is the most likely diagnosis? And why? Use the bone marrow biopsy and the CBC results included to justify the answer. -Justify the diagnosis using the morphology of the cells listed in CBC section. Compare it with the reference ranges.
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Look at the attached image. What is the most likely diagnosis? And why? Use the bone marrow biopsy and the CBC results included to justify the answer.
-Justify the diagnosis using the morphology of the cells listed in CBC section. Compare it with the reference ranges.
Transcribed Image Text:History:
51 year old male, general health reported as OK, good diet perhaps a little loss of
appetite, regular exercise a little fatigued usually explained by 'over doing it at the gym'.
Patient was seen by his GP for a routine preoperative check before dental surgery. He was
found to have low haemoglobin and large left upper quadrant mass.
Complete blood count (CBC):
3.36 x 1012/L
9.3 x 10/L
5.9 x 10°/L
RBC
WBC
PLT
HGB
10.9
g/dL
HCT
31.2
MCV
92.8
fL
Neutrophils
Lymphocytes
Abnormal cells
14%
15%
71% (shown)
Further Laboratory Studies
Bone marrow biopsy:
Aspirate: A small
abnormal cells similar to those in the blood smear.
unt of fluid was aspirated, and showed 78.1%
Sections: Hypocellular with a diffuse loosely structured infiltrate of
mononuclear cells. Increased areas of fibrosis.
Cytochemistry: Tartrate resistant acid phosphatase (TRAP) stain of
abnormal cells: positive
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