WHAT IF? Patients with diseases such as heart disease or Alzheimer’scould have their own skin cells reprogrammed to become iPS cells. Once procedures have been developed for converting iPS cells into heart or nervoussystem cells, the patients’ own iPS cells might be used to treat their disease.When organs are transplanted from a donor to a diseased recipient, the recipient’s immune system may reject the transplant, a dangerous condition. Wouldusing iPS cells be expected to carry the same risk? Why or why not? Giventhat these cells are actively dividing, undifferentiated cells, what risks mightthis procedure carry?
WHAT IF? Patients with diseases such as heart disease or Alzheimer’s
could have their own skin cells reprogrammed to become iPS cells. Once procedures have been developed for converting iPS cells into heart or nervous
system cells, the patients’ own iPS cells might be used to treat their disease.
When organs are transplanted from a donor to a diseased recipient, the recipient’s immune system may reject the transplant, a dangerous condition. Would
using iPS cells be expected to carry the same risk? Why or why not? Given
that these cells are actively dividing, undifferentiated cells, what risks might
this procedure carry?
Step 1
Induced pluripotent stem cells is a kind of pluripotent cell that can be made from adult somatic cells by genetic reprogramming genes like-Oct3 / 4, Sox2, c-Myc, and Klf4. The genes are encoded with transcription factor that can change somatic cell into pluripotent stem cells.
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