RCA1 is a tumor suppressor gene. BRCA1* is the symbol for the non-mutant or wild-type form of the gene. art1. A woman has inherited a mutant BRCA1 allele. Her genotype is BRCA1*/BRCA1'.How many copies of the wild-type BRCA1 allele and the mutant BRCA1 allele would ou expect to find in each of her non-cancerous cells? art 2. How many copies of the wild-type BRCA1* allele and the mutant BRCA1 allele would you expect to find in each of her cancerous cells? art 3. Describe whether mutant BRCA1 acts in a recessive or dominant fashion in a cell. art 4. If you analyze this woman's eggs, how many copies of the wild-type BRCA1* allele and the mutant BRCA1° allele would you expect to find in each egg? What is the chand

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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BRCA1 is a tumor suppressor gene. BRCA1* is the symbol for the non-mutant or wild-type form of the gene.
Part1. A woman has inherited a mutant BRCA1 allele. Her genotype is BRCA1*/BRCA1". How many copies of the wild-type BRCA1+ allele and the mutant BRCA1 allele would
you expect to find in each of her non-cancerous cells?
Part 2. How many copies of the wild-type BRCA1* allele and the mutant BRCA1¯ allele would you expect to find in each of her cancerous cells?
Part 3. Describe whether mutant BRCA1° acts in a recessive or dominant fashion in a celI.
Part 4. If you analyze this woman's eggs, how many copies of the wild-type BRCA1* allele and the mutant BRCA1¯ allele would you expect to find in each egg? What is the chance
that she passes on the mutant form of BRCA1 to her egg and then to potential offspring?
Transcribed Image Text:BRCA1 is a tumor suppressor gene. BRCA1* is the symbol for the non-mutant or wild-type form of the gene. Part1. A woman has inherited a mutant BRCA1 allele. Her genotype is BRCA1*/BRCA1". How many copies of the wild-type BRCA1+ allele and the mutant BRCA1 allele would you expect to find in each of her non-cancerous cells? Part 2. How many copies of the wild-type BRCA1* allele and the mutant BRCA1¯ allele would you expect to find in each of her cancerous cells? Part 3. Describe whether mutant BRCA1° acts in a recessive or dominant fashion in a celI. Part 4. If you analyze this woman's eggs, how many copies of the wild-type BRCA1* allele and the mutant BRCA1¯ allele would you expect to find in each egg? What is the chance that she passes on the mutant form of BRCA1 to her egg and then to potential offspring?
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