Research how the CD28/B7 and CTLA-4/B7 interactions are being targeted in the development of new therapeutic drugs. - Briefly summarize the functions of CD28 and CTLA-4 and summarize in concept why they represent attractive therapeutic targets. - What kinds of diseases could potentially be treated by such drugs? Explain why. Identify at least one new drug that is either already in use or under development which targets either of these molecules; and include the following information: the company or research institute, the stage of development of the drug, the disease that is being treated. - What alternative therapies if any exist for this disease? - Does this drug offer a better alternative to current treatments? Why or why not? - What do you think are the pros/cons with the use of this drug? - At the end of your report include an open-ended and provocative question that will inspire your classmates to respond to your report.
Research how the CD28/B7 and CTLA-4/B7 interactions are being targeted in the development of new therapeutic drugs. - Briefly summarize the functions of CD28 and CTLA-4 and summarize in concept why they represent attractive therapeutic targets. - What kinds of diseases could potentially be treated by such drugs? Explain why. Identify at least one new drug that is either already in use or under development which targets either of these molecules; and include the following information: the company or research institute, the stage of development of the drug, the disease that is being treated. - What alternative therapies if any exist for this disease? - Does this drug offer a better alternative to current treatments? Why or why not? - What do you think are the pros/cons with the use of this drug? - At the end of your report include an open-ended and provocative question that will inspire your classmates to respond to your report.
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Transcribed Image Text:Research how the CD28/B7 and CTLA-4/B7 interactions
are being targeted in the development of new
therapeutic drugs. - Briefly summarize the functions of
CD28 and CTLA-4 and summarize in concept why they
represent attractive therapeutic targets. - What kinds of
diseases could potentially be treated by such drugs?
Explain why. Identify at least one new drug that is
either already in use or under development which
targets either of these molecules; and include the
following information: the company or research
institute, the stage of development of the drug, the
disease that is being treated. - What alternative
therapies if any exist for this disease? - Does this drug
offer a better alternative to current treatments? Why or
why not? - What do you think are the pros/cons with
the use of this drug? - At the end of your report include
an open-ended and provocative question that will
inspire your classmates to respond to your report.
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