Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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What does methyl b-cyclodextrin do to cell membranes? Based on this, explain the
effect of this compound on Trypan Blue exclusion or lack thereof.
Expert Solution
Step 1
Methyl β cyclodextrin is a heptasaccharide, which is soluble in water and have more affinity to cholesterol due to presence of hydrophobic core.
*Cyclodextrins are cyclic oligosaccharides consisting of 6 or 7 or 8 glucopyranose units referred to as α and β or γ cyclodextrins respectively.
*cyclodextrins agents helps to increase the aqueous solubility of active substances poorly soluble in water in order to increase their bioavailability.
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