v A 1. Sar1 GEF v B 2. protein with an N-SIG (only) in a class B yeast sec mutant 3. cis-Golgi v-SNARE 4. COPII

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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The image contains a diagram labeled with letters A, B, C, and D. It appears to represent a cellular structure involved in protein localization. The diagram depicts a sequence of membrane-bound compartments, possibly indicating a section of the endoplasmic reticulum and Golgi apparatus.

### Diagram Explanation:
- **A:** Situated on the endoplasmic reticulum, indicating potential accumulation points for proteins.
- **B and C:** Located at junctions or transitional regions, possibly suggesting areas of protein sorting or modification.
- **D:** Found on curved membrane protrusions or vesicles, representing sites for protein trafficking or secretion.

The arrows show the movement or direction of proteins through these compartments, indicating flows towards different parts of the cellular structure. This suggests a process of protein maturation or transport occurring within a wild-type cellular context.
Transcribed Image Text:The image contains a diagram labeled with letters A, B, C, and D. It appears to represent a cellular structure involved in protein localization. The diagram depicts a sequence of membrane-bound compartments, possibly indicating a section of the endoplasmic reticulum and Golgi apparatus. ### Diagram Explanation: - **A:** Situated on the endoplasmic reticulum, indicating potential accumulation points for proteins. - **B and C:** Located at junctions or transitional regions, possibly suggesting areas of protein sorting or modification. - **D:** Found on curved membrane protrusions or vesicles, representing sites for protein trafficking or secretion. The arrows show the movement or direction of proteins through these compartments, indicating flows towards different parts of the cellular structure. This suggests a process of protein maturation or transport occurring within a wild-type cellular context.
### Diagram Explanation:

This diagram depicts a section of cellular organelles, likely representing the endoplasmic reticulum and Golgi complex, highlighting the process of vesicular transport. Several sections are labeled with letters (A, B, C, D), and vesicles are shown budding off and moving toward the Golgi.

**Label Descriptions:**
- **A:** Represents a structure likely part of the endoplasmic reticulum.
- **B and C:** Illustrate regions where vesicular transport is initiated. Arrows indicate the direction of vesicle movement.
- **D:** Suggests areas of the Golgi complex involved in further processing.

**Vesicle Formation and Transport:**
The arrows and dotted lines represent the budding and movement of vesicles. This shows how materials are packaged and transported between the organelles.

### Key Components:

1. **Sar1 GEF:** A guanine nucleotide exchange factor essential for the activation of Sar1, which initiates COPII vesicle formation.
2. **Protein with an N-SIG (only) in a class B yeast sec mutant:** Indicates a specific protein pathway affected in a mutant yeast class, relevant for studying secretion pathways.
3. **cis-Golgi v-SNARE:** A vesicular SNARE protein important for the fusion of vesicles with the Golgi.
4. **COPII:** Coat Protein Complex II, responsible for vesicle formation from the endoplasmic reticulum.

### Interactive Elements:

Below the diagram, a list provides different options (A, B, C, D) that can be selected, likely as part of an educational interaction to test understanding of vesicular transport role-playing in cellular processes.
Transcribed Image Text:### Diagram Explanation: This diagram depicts a section of cellular organelles, likely representing the endoplasmic reticulum and Golgi complex, highlighting the process of vesicular transport. Several sections are labeled with letters (A, B, C, D), and vesicles are shown budding off and moving toward the Golgi. **Label Descriptions:** - **A:** Represents a structure likely part of the endoplasmic reticulum. - **B and C:** Illustrate regions where vesicular transport is initiated. Arrows indicate the direction of vesicle movement. - **D:** Suggests areas of the Golgi complex involved in further processing. **Vesicle Formation and Transport:** The arrows and dotted lines represent the budding and movement of vesicles. This shows how materials are packaged and transported between the organelles. ### Key Components: 1. **Sar1 GEF:** A guanine nucleotide exchange factor essential for the activation of Sar1, which initiates COPII vesicle formation. 2. **Protein with an N-SIG (only) in a class B yeast sec mutant:** Indicates a specific protein pathway affected in a mutant yeast class, relevant for studying secretion pathways. 3. **cis-Golgi v-SNARE:** A vesicular SNARE protein important for the fusion of vesicles with the Golgi. 4. **COPII:** Coat Protein Complex II, responsible for vesicle formation from the endoplasmic reticulum. ### Interactive Elements: Below the diagram, a list provides different options (A, B, C, D) that can be selected, likely as part of an educational interaction to test understanding of vesicular transport role-playing in cellular processes.
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