Answered: True or false? The E2 component of the…

Science

Biochemistry

True or false? The E2 component of the Pyruvate Dehydrogenase complex binds NAD+ in its active site.

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter19: The Tricarboxylic Acid Cycle

Section: Chapter Questions

Problem 22P: Study Figure 19.18 and decide which of the following statements is false. Pyruvate dehydrogenase is...

See similar textbooks

Related questions

Q: In muscle cells upon heavy exertion, oxygen can be lacking and aerobic metabolism leads to…

A: Cellular respiration is the set of metabolic activities and reactions that takes place in the cells…

Q: NADH is generated by all of the following Krebs cycle enzymes except: alpha-ketoglutarate…

A: Citric acid cycle, also known as Krebs cycle includes a series of chemical reactions used by…

Q: Lactate dehydrogenase (LDH) plays an essential role in an exercising muscle, especially when the…

A: During cellular respiration, respiratory substrates like glucose may undergo complete or…

Q: From the complete oxidation of glucose (glucose > 6CO2), how may total NADH electron carriers are…

A: The metabolic pathway that breaks down glucose and produces ATP is known as cellular respiration.…

Q: When glycogen is degraded (catabolized), all of the following occur in both liver and muscle EXCEPT…

A: Glycogenolysis is the process of breaking down the stored glycogen into simple sugar units. It…

Q: Why is oxaloacetate depletion from the TCA cycle important for the initiation of ketogenesis? What…

A: The TCA cycle is a central metabolic pathway that occurs in the mitochondria of cells and is…

Q: Identify the Krebs cycle enzyme that consumes a six-carbon substrate molecule, producing a…

A: Kreb's cycle or tricarboxylic acid cycle is a aerobic respiration process in which acetyl CoA is…

Q: Of the allosteric enzymes listed below, which are suppressed by NADH? Select all that apply. the…

A: Enzymes catalyse biochemical reactions. Substrate binds to the enzyme's active site and is converted…

Q: The reaction is reversible. Check all that apply. acetyl CoA lactate ethanol

A: “Since you have asked multiple questions, we will solve the first question for you. If you want any…

Q: Please choose the right answer from the bold text In the malate dehydrogenase-catalyzed reaction,…

A: Citric acid cycle also known as tricarboxylic acid cycle or Kreb's cycle occurs in mitochondrial…

Q: Explain Why Synthesizing Glucose from Pyruvate in the Anabolic Process of Gluconeogenesis requires…

A: “Since you have posted a question with multiple sub-parts, we will solve first three subparts for…

Q: Pyruvate dehydrogenase catalyzes the conversion of pyruvate to acetyl CoA. In this reaction, one…

A: Pyruvate dehydrogenase Enzyme is a complex of three enzymes that are important for decarboxylation…

Q: QUESTION 34 Which of the following represents a reaction that could be used to refill the TCA cycle…

A: TCA cycle occurs in the matrix of mitochondria. The net result of Kreb cycle is that for each acetyl…

Q: CH3CH2OH + NAD+ --> CH3CHO + NADH +H+ Explain how this reaction inhibits the production of pyruvate…

A: Ethanol is mostly consumed by humans, which gets metabolized readily in the liver. It is generally…

Q: Can you please pick the right answer in each parentheses (a) to (e)?

A: Answer. Pyruvate dehydrogenase complex is an assembly of three individual enzymes. It is the…

Q: FAD is a stronger oxidant than NAD*; FAD has a higher standard reduction potential than NAD*. Yet in…

A: Flavin adenine dinucleotide (FAD) is a redox-active coenzyme associated with various proteins, which…

Q: In the pyruvae dehydrogensae complex, acetyl-coa is released by the dihydrolipoyl transacetylase…

A: Pyruvate dehydrogenase complex converts pyruvate to acetyl CoA by oxidative decarboxylation.…

Q: Figure 17.9 shows the steps in the pyruvate dehydrogenase complex reaction cycle. A key product,…

A: Glycolysis converts glucose to pyruvate. Pyruvate is then converted to acetyl-CoA via pyruvate…

Q: Help me understand this…I’m confused

A: Refer to the solution

Q: . In deciding which form of isocitrate dehydrogenase plays the more important role in the citric…

A: The citric acid cycle is also known as TCA cycle. It is a series of chemical reactions used by all…

Q: The first step of gluconeogenesis involves the carboxylation of pyruvate and has a large negative…

A: Carboxylation is the process of adding a carboxylate (COO-) group into a molecule. Upon…

Q: Which of the following is absolutely true in case of arsenate poisoning

A: Arsenite is a toxic heavy metal; its consumption results in many health hazards. Impairment of…

Q: Which of the following catalyzes a step that does NOT produce CO2? Group of answer choices…

A: Malate dehydrogenase catalyzes a step that does NOT produce CO2.Malate dehydrogenase catalyzes the…

Question

True or false?

The E₂ component of the Pyruvate Dehydrogenase complex binds NAD⁺ in its active site.

Expert Solution

This question has been solved!

Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.

This is a popular solution!

SEE SOLUTION Check out a sample Q&A here

Step 1

Step 2

Step 3

Step 4

Trending now

This is a popular solution!

Step by step

Solved in 4 steps with 1 images

SEE SOLUTION Check out a sample Q&A here

Similar questions

Briefly describe the dual role of lipoic acid in the pyruvate dehydrogenase complex
During Krebs cycle, the conversion of isocitrate to alpha-keto glutarate involves all of the following reactions/mechanisms except Reduction of isocitrate Reduction of NAD+ Decarboxylation of isocitrate Oxidation of isocitrate
Which of the following is NOT a cofactor for the pyruvate dehydrogenase complex? Lipoate COA FAD NADP+ All of the above are cofactors for the PDH complex.
A patient exhibiting all the symptoms of beriberi is placed on a thiamine-enriched diet; however, the symptoms do not disappear. Genetic screening suggests a defect in pyruvate dehydrogenase phosphatase. Briefly explain why the genetic defect caused beriberi symptoms andy why thiamine supplementation had no effect.
Of the allosteric enzymes listed below, which are suppressed by NADH? Select all that apply. the pyruvate dehydrogenase complex a-ketoglutarate dehydrogenase complex U isocitrate dehydrogenase pyruvate kinase Ophosphofructokinase hexokinase Oglucokinase
Which of the following is true about comparing the α-ketoglutarate dehydrogenase complex and the pyruvate dehydrogenase complex? Group of answer choices They catalyze reactions that produce the exact same set of products They are both dehydrogenase complexes, but have very different structures They both catalyze reactions that oxidize NADH to NAD+ They both use the same E3 enzyme component Which of the following best describes stage 2 of the citric acid cycle? Group of answer choices ATP production by the electron transport chain production of acetyl CoA regeneration of oxaloacetate release of 2 carbons as carbon dioxide
Pyruvate dehydrogenase activity is regulated in part by the concentration of acetyl COA. Name three metabolic pathways that can effect acetyl CoA levels, thus effecting the regulation of the Kreb Cycle.
CH3CH2OH + NAD+ --> CH3CHO + NADH +H+ Explain how this reaction inhibits the production of pyruvate from lactate. Why does this lead to low blood glucose levels? please and thank you
When pyruvate dehydrogenase complex is phosphorylated, it is (active or inactive)
Briefly describe the role and location of each cofactor/coenzyme involved in the pyruvate dehydrogenase reaction.
The citric acid cycle is mainly controlled at the first two NADH-producing reactions catalyzed by ___________ and ___________, respectively. Group of answer choices isocitrate dehydrogenase; alpha-ketoglutarate dehydrogenase complex pyruvate dehydrogenase complex; alpha-ketoglutarate dehydrogenase complex alpha-ketoglutarate dehydrogenase complex; malate dehydrogenase isocitrate dehydrogenase; malate dehydrogenase pyruvate dehydrogenase complex; isocitrate dehydrogenase
which statements are False?