To hold bacterial DNA in a more compact configuration, specificproteins must bind to the DNA and stabilize its conformation.Several different proteins are involved in this process. Some of theseproteins, such as H-NS, have been referred as histone-like, due totheir functional similarity to the histone proteins found in eukaryotes.Based on your knowledge of eukaryotic histone proteins, whatbiochemical properties would you expect bacterial histone-likeproteins to have?

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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 To hold bacterial DNA in a more compact configuration, specific
proteins must bind to the DNA and stabilize its conformation.
Several different proteins are involved in this process. Some of these
proteins, such as H-NS, have been referred as histone-like, due to
their functional similarity to the histone proteins found in eukaryotes.
Based on your knowledge of eukaryotic histone proteins, what
biochemical properties would you expect bacterial histone-like
proteins to have?

Expert Solution
Step 1

 The DNA ( deoxyribonucleic acid) is the genetic material of the organism. In Eukaryotic organisms the DNA may be of several metres in length. However the size of the nucleus is several micrometres in diameter. The DNA undergoes chromosomal packaging which enables it to form a content structure that may fit into the nucleus of the organism. In doing so the DNA wraps around the nuclear proteins commonly known as histones to form The structures known as chromatins.

Step 2

The bacterial histone-like proteins have similar functions like the stones and Eukaryotic  chromosome.

  • The bacterial histone-like proteins are small in structure.
  • They  are basic in nature and are positively charged which allows the DNA to wrap tightly around them. 
  • They bind to the DNA sequence dependent manner unlike other proteins which bind to the DNA at specific sequence.
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