There are five substitution mutations in the dark-colored mutant Mc1r gene. Compare the DNA sequence of the light-colored wild-type Mc1r gene with the DNA sequence of the dark-colored mutant Mc1r gene. Indicate the locations of the five mutations by changing the font color to YELLOW for the five single DNA nucleotides that are mutated in the mutant Mc1r gene table. Using the information in the introduction, determine whether each of these mutations is a silent, missense, or nonsense mutation. Using the mutant Mc1r gene data, fill in the columns (including DNA, mRNA, and amino acid) in gene table 2 that contain a silent mutation with BLUE. Likewise, fill in the columns that contain a missense mutation with RED. Shade any columns that contain nonsense mutations with GREEN.
There are five substitution mutations in the dark-colored mutant Mc1r gene. Compare the DNA sequence of the light-colored wild-type Mc1r gene with the DNA sequence of the dark-colored mutant Mc1r gene. Indicate the locations of the five mutations by changing the font color to YELLOW for the five single DNA nucleotides that are mutated in the mutant Mc1r gene table. Using the information in the introduction, determine whether each of these mutations is a silent, missense, or nonsense mutation. Using the mutant Mc1r gene data, fill in the columns (including DNA, mRNA, and amino acid) in gene table 2 that contain a silent mutation with BLUE. Likewise, fill in the columns that contain a missense mutation with RED. Shade any columns that contain nonsense mutations with GREEN.
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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There are five substitution mutations in the dark-colored mutant Mc1r gene. Compare the DNA sequence of the light-colored wild-type Mc1r gene with the DNA sequence of the dark-colored mutant Mc1r gene. Indicate the locations of the five mutations by changing the font color to YELLOW for the five single DNA nucleotides
that are mutated in the mutant Mc1r gene table.
Using the information in the introduction, determine whether each of these mutations is a silent, missense, or nonsense mutation.
Using the mutant Mc1r gene data, fill in the columns (including DNA, mRNA, and amino acid) in gene table 2 that contain a silent mutation with BLUE.
Likewise, fill in the columns that contain a missense mutation with RED.
Shade any columns that contain nonsense mutations with GREEN.
Transcribed Image Text:GENE TABLE 2: (DARK COAT-COLOR PHENOTYPE)
DNA
mRNA
Amino
Acid
DNA
mRNA
Amino
Acid
DNA
DNA
015
mRNA
Amino
Acid
CAA
GUU
105
Valine Threonine
CCG
GGC
154
mRNA
UUC
Amino Phenylalani
Acid
ne
AAG
230
TGT
GCT
ACA
CGA
GTG
CAC
TCG
Glycine Histidine Serine Isoleucine
AGC
Serine
ΝΑ
mRNA
Amino
Acid
CCA
GGU
GGG
Arginine Glycine
CCC
Proline
AGG
ATA
UAU
UCC AUU
209
CGT
GCA
Alanine
AAG
Tyrosine Valine
CCG
UUC
Phenylalani
ne
GGC
TAA
Glycine
CAG
GUC
GUU
TTA
CGA
AAU
GCU
Alanine
AGG
UCC
Serine
TGG
ACC
Valine Leucine
GAC
CUG
GTG
CCA
CAC
GGU
CCG
Glycine Valine
GGC
Threonine Leucine
Glycine
GAG
CUC
212
GGU
Glycine
CAG
GUC
CAC
GUG
Valine
Asparagine Histidine
112
TTA
AAU
CCA
GGU
Glycine
Asparagine Proline
AGG
UCC
022
Serine
TAA
AUU
Isoleucine
GGG
CCC
161
GAA
CUU
Leucine
237
GGA
CCU
Proline
Transcribed Image Text:GENE TABLE 1: (LIGHT COAT-COLOR PHENOTYPE)
015
DNA
mRNA
Amino
Acid
DNA
mRNA
Amino
Acid
DNA
DNA
CAA
mRNA
Amino
Acid
GUU
105
CCG
GGC
Valine Threonine Proline
154
mRNA
UUC
Amino Phenylalani
Acid
ne
AAG
230
TGT
GCT
ACA
CGA
GTG
CAC
AUU
Glycine Histidine Serine Isoleucine
GCG
CGC
DNA
mRNA
Amino
Acid
GGG
CCC
CCC
GGG
Arginine Tyrosine
Arginine Glycine
AGG
UCC
ATA
UAU
209
TGT
ACA
Threonine
CCG
AAG
GGC
UUC
Phenylalani
ne
TAA
CAG
GUC
CAA
GUU
CGA
TTA
GCU
AAU
Alanine
AGC
UCG
Valine Threonine
Serine
TGG
ACC
GAC
Valine Leucine
CUG
GTG
CAC
Glycine Asparagine Histidine
TCA
AGU
Serine
CCG
GGC
GAG
CUC
212
CCA
GGU
Glycine
Glycine Asparagine
CAG
CAC
GUC
GUG
Valine
Valine
112
TTA
AAU
CCA
GGU
AGG
UCC
022
Leucine Glycine Leucine
Serine
TAA
AUU
Isoleucine
GGG
CCC
Proline
161
GAA
CUU
237
GGA
CCU
Proline
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