The X-linked gene responsible for DMD encodes a protein called dystrophin that is required for muscle function. Dystrophin protein is not secreted—it remains inthe cells that produce it. Given what you know aboutBarr body formation, do you think that females heterozygous for the recessive DMD disease allele could havethe disease in some parts of their bodies and not others?

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
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The X-linked gene responsible for DMD encodes a protein called dystrophin that is required for muscle function. Dystrophin protein is not secreted—it remains in
the cells that produce it. Given what you know about
Barr body formation, do you think that females heterozygous for the recessive DMD disease allele could have
the disease in some parts of their bodies and not others?

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