Ichthyosis is a rare X-linked recessive disorder that is characterized by scaling of the skin around the neck and lower extremities. A young couple, Bart and Jenny, are expecting a child and are aware there might be a chance that their child could be affected by this disorder. Jenny (the wife) has ichthyosis while Bart (her husband) is unaffected and completely normal with respect to the allele responsible for this disorder. Both Bart and Jenny were Biology majors as undergraduates. Knowing a little about the pattern of X-linked recessive inheritance, Bart and Jenny were concerned when ultrasound revealed that they would be having a son. However, genetic testing performed shortly after birth revealed that their newborn son, Mark, did not have ichthyosis. A) Define the alleles associated with X-linked recessive ichthyosis, using the type of genetic notation utilized in the class for disorders showing a similar pattern of inheritance. (i) Ichthyosis allele: XY (ii) Normal allele: XX B) Using the alleles that you defined in Part A, list the genotype o
Ichthyosis is a rare X-linked recessive disorder that is characterized by scaling of the skin around the neck and lower extremities. A young couple, Bart and Jenny, are expecting a child and are aware there might be a chance that their child could be affected by this disorder. Jenny (the wife) has ichthyosis while Bart (her husband) is unaffected and completely normal with respect to the allele responsible for this disorder.
Both Bart and Jenny were Biology majors as undergraduates. Knowing a little about the pattern of X-linked recessive inheritance, Bart and Jenny were concerned when ultrasound revealed that they would be having a son. However, genetic testing performed shortly after birth revealed that their newborn son, Mark, did not have ichthyosis.
A) Define the alleles associated with X-linked recessive ichthyosis, using the type of genetic notation utilized in the class for disorders showing a similar pattern of inheritance.
(i) Ichthyosis allele: XY (ii) Normal allele: XX
B) Using the alleles that you defined in Part A, list the genotype of Bart (Baby Mark’s father) and of Jenny (Baby Mark’s mother).
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- Genotype of Bart (the baby’s father):
- Genotype of Jenny (the baby’s mother):
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