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Label all individuals with the correct genotype. If you are not certain of the gentotype, list all possible geneotypes with their associated probabilities (based on the genotypes of their parents)

Label all individuals with the correct genotype. If you are not certain of the gentotype, list all possible geneotypes with their associated probabilities (based on the genotypes of their parents)

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Label all individuals with the correct genotype. If you are not certain of the gentotype, list all possible geneotypes with their associated probabilities (based on the genotypes of their parents)

### Pedigree Analysis of Hemophilia in a Family This pedigree chart represents the inheritance pattern of hemophilia, an X-linked recessive disorder, within a family across four generations. #### Diagram Explanation: - **Squares** represent males. - **Circles** represent females. - **Shaded shapes** indicate individuals affected by hemophilia. - **Unshaded shapes** represent unaffected individuals. #### Generations: - **Generation I**: - Contains a married couple with no affected individuals. - **Generation II**: - Consists of multiple siblings, two of whom are males affected by hemophilia (individuals II-1 and II-2). - The rest are unaffected males and females. - **Generation III**: - Includes affected males (III-3, III-4, and III-6) and unaffected relatives. - Female III-5 is connected to an affected male (III-4) through marriage. - **Generation IV**: - Shows descendants of III-4 and III-5, depicting several unaffected individuals. #### Possible Genotypes: - **Males**: - X\(^H\)/Y: Affected - X\(^+\)/Y: Unaffected - **Females**: - X\(^+\)/X\(^+\): Unaffected - X\(^+\)/X\(^H\): Carrier (phenotypically unaffected) - X\(^H\)/X\(^H\): Affected This pattern of inheritance exemplifies typical X-linked recessive traits, where males are more often affected due to having only one X chromosome. Carrier females can pass the affected gene to their offspring, potentially resulting in affected sons if they inherit the X\(^H\) chromosome.
Transcribed Image Text:### Pedigree Analysis of Hemophilia in a Family This pedigree chart represents the inheritance pattern of hemophilia, an X-linked recessive disorder, within a family across four generations. #### Diagram Explanation: - **Squares** represent males. - **Circles** represent females. - **Shaded shapes** indicate individuals affected by hemophilia. - **Unshaded shapes** represent unaffected individuals. #### Generations: - **Generation I**: - Contains a married couple with no affected individuals. - **Generation II**: - Consists of multiple siblings, two of whom are males affected by hemophilia (individuals II-1 and II-2). - The rest are unaffected males and females. - **Generation III**: - Includes affected males (III-3, III-4, and III-6) and unaffected relatives. - Female III-5 is connected to an affected male (III-4) through marriage. - **Generation IV**: - Shows descendants of III-4 and III-5, depicting several unaffected individuals. #### Possible Genotypes: - **Males**: - X\(^H\)/Y: Affected - X\(^+\)/Y: Unaffected - **Females**: - X\(^+\)/X\(^+\): Unaffected - X\(^+\)/X\(^H\): Carrier (phenotypically unaffected) - X\(^H\)/X\(^H\): Affected This pattern of inheritance exemplifies typical X-linked recessive traits, where males are more often affected due to having only one X chromosome. Carrier females can pass the affected gene to their offspring, potentially resulting in affected sons if they inherit the X\(^H\) chromosome.
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