The Robinson carbonyl coupling reactions, the Michael reaction and the intramolecular aldol condensation. The most common partners in the li donor (such as a cyclic ketone, a β-keto ester, an enamine, or a β-diketone) and an α,β-unsaturated ketone acceptor. The product is a substituted 2-cyclohexenone derivative annulation is a combination of two reaction are a nucleophi Draw the structures of the nucleophilic B-keto ester and the α,β-unsaturated ketone acceptor that were combined in a Robinson annulation to give the following product Ph Ph Ph Ph CO2Et Draw the B-keto ester as an ethyl ester

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The Robinson annulation is a combination of two carbonyl coupling reactions, the Michael reaction and the intramolecular aldol condensation. The most common partners in the reaction are a nucleophilic donor (such as a cyclic ketone, a β-keto ester, an enamine, or a β-diketone) and an α,β-unsaturated ketone acceptor. The product is a substituted 2-cyclohexenone derivative.

Draw the structures of the nucleophilic β-keto ester and the α,β-unsaturated ketone acceptor that were combined in a Robinson annulation to give the following product:

 
  • Draw the β-keto ester as an ethyl ester,
The Robinson
carbonyl coupling reactions, the Michael reaction and
the intramolecular aldol condensation. The most
common partners in the li
donor (such as a cyclic ketone, a β-keto ester, an
enamine, or a β-diketone) and an α,β-unsaturated ketone
acceptor. The product is a substituted 2-cyclohexenone
derivative
annulation is a combination of two
reaction are a nucleophi
Draw the structures of the nucleophilic B-keto ester and
the α,β-unsaturated ketone acceptor that were combined
in a Robinson annulation to give the following product
Ph
Ph
Ph
Ph
CO2Et
Draw the B-keto ester as an ethyl ester
Transcribed Image Text:The Robinson carbonyl coupling reactions, the Michael reaction and the intramolecular aldol condensation. The most common partners in the li donor (such as a cyclic ketone, a β-keto ester, an enamine, or a β-diketone) and an α,β-unsaturated ketone acceptor. The product is a substituted 2-cyclohexenone derivative annulation is a combination of two reaction are a nucleophi Draw the structures of the nucleophilic B-keto ester and the α,β-unsaturated ketone acceptor that were combined in a Robinson annulation to give the following product Ph Ph Ph Ph CO2Et Draw the B-keto ester as an ethyl ester
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