The quality problem A central theme in biochemistry is that protein function is determined by protein structure. A protein with the correct primary sequence can undergo misfolding and will not be useful, can even be toxic. Scientists use the simple idea of movement of objects in a medium (large things move slower and small things move faster) to quality check for proteins. Come up with an idea on how will you get a large yield of protein for experimentation?

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
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The quality problem

A central theme in biochemistry is that protein function is determined by protein structure. A

protein with the correct primary sequence can undergo misfolding and will not be useful, can even

be toxic. Scientists use the simple idea of movement of objects in a medium (large things move

slower and small things move faster) to quality check for proteins. Come up with an idea on how

will you get a large yield of protein for experimentation?

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