The molecular ion region in the mass spectrum of a large molecule, such as a protein, consists of a cluster of peaks differing by 1 Da. This pattern occurs because a molecule with many atoms has a high probability of containing one or several atoms of 13 C, 15N, 180, 2H and 34 S. The probability of finding a molecule with only 12C, 14N, 160, 'H and 32S may be so small that the nominal molecular ion is not observed. The electrospray mass spectrum of the rat protein interleukin-8 consists of a series of clusters of peaks arising from intact molecular ions with different charge. One cluster has peaks at m/z 1961.12, 1961.35, 1961.63, 1961.88, 1962.12 (tallest peak), 1962.36, 1962.60, 1962.87, 1963.10, 1963.34, 1963.59,1963.85, and 1964.09. These peaks correspond to isotopic ions differing by 1 Da. From the observed peak separation, find the charge of the ions in this cluster. Z=

The molecular ion region in the mass spectrum of a large molecule, such as a protein, consists of a cluster of peaks differing by 1 Da. This pattern occurs because a molecule with many atoms has a high probability of containing one or several atoms of 13 C, 15N, 180, 2H and 34 S. The probability of finding a molecule with only 12C, 14N, 160, 'H and 32S may be so small that the nominal molecular ion is not observed. The electrospray mass spectrum of the rat protein interleukin-8 consists of a series of clusters of peaks arising from intact molecular ions with different charge. One cluster has peaks at m/z 1961.12, 1961.35, 1961.63, 1961.88, 1962.12 (tallest peak), 1962.36, 1962.60, 1962.87, 1963.10, 1963.34, 1963.59,1963.85, and 1964.09. These peaks correspond to isotopic ions differing by 1 Da. From the observed peak separation, find the charge of the ions in this cluster. Z=

Chemistry & Chemical Reactivity

10th Edition

ISBN:9781337399074

Author:John C. Kotz, Paul M. Treichel, John Townsend, David Treichel

Publisher:John C. Kotz, Paul M. Treichel, John Townsend, David Treichel

Chapter2: Atoms Molecules And Ions

Section: Chapter Questions

Problem 100PS

See similar textbooks

Similar questions

4. Halogenated compounds are particularly easy to identify by their mass spectra because chlorine and bromine occur naturally as mixtures of two abundant isotopes. Chlorine occurs as "CI (75.8%) and "CI (24.2%). Ignore the presence of "C isotopes. For the compound, C,H,Cl;: a) At what masses do the molecular ions occur? b)What are the percentages of cach molecular ion?
2. In a mass spectrum of a compound, the following data (intensity) is given. M+ = 80, M+ +1 = 8.8, M+ +2 = 26. This compound will have carbons and will contain a a. 8, sulfur b. 9, silicon c. 10, chlorine d. 11, bromine
The molecular weight of compound D is calculated to be 359.22 g/mol., However, the mass spectrum contains two peakS, with m/z 358.02 and m/z @360.02, in a approximately a 1:1 ratio. Explain this observation. HTML Editorg
How do I predict the M, M+2. and M+4 with this information?
3. Bromine, Br2 Consider the fragmentation of diatomic compounds. For example, 158Br2 will give a signal at 79 for 79Br and one at 79 for Br. Br has two naturally occurring isotopes, the 79 isotope and the 81 isotope. Determine the origin (formula) of each of the signals for the mass spectrum of molecular bromine. Example, 158Br2 is equal to 79Br79Br. Relative Abundance 90 80 70 60 50 30 20 10 D 79 81 158 160 162 62 Mass (amu) Figure 4. Mass Spectrum of Br. Mass Number Measurement (cm) Abundance Formula Calculations XXXX XXXX XXXX XXXX XXXX XXXX
For the following mass spectra determine: presence or absence of Cl and Br, molecular weight, of it is consistent with an odd number or zero/even number of N atoms, parent peak, base peak.
Mass spectroscopic. What is the isotopic peak pattern of each : Organic compound with 2 bromine atoms. Organic compound with 2 chlorine atoms.
The mass spectrum below corresponds to acetone (C,H,O). What is the likely chemical composition of the ion that generates the tallest peak in the spectrum? A CH; B C₂H₂O* C C₂H₂0 D CO* Adve MALUPECTUR 14
Which of the following statements is correct? O A. Atomic emission detector is suitable for analyzing hydrocarbon compounds. B. The best carrier gas for a thermal conductivity detector is nitrogen. O C. Chlorine containing compounds are best analyzed by using an electron capture detector. O D. Equimolar amount of C6H14 and C3H8 should produce the same signals using a flame ionization detector. O E. Mass spectrometry detector is nondestructive.
Cyclohexene and 2 hexyne both have the molecular formula C6H10. How would you use infrared spectroscopy to distinguish between these two compounds?
A compound containing only carbon, nitrogen, oxygen, and hydrogen contains four carbon atoms. If the M+ peak in its mass spectrum appears at m/z = 87, then how many nitrogen atoms does it contain?
Using the rule of 13, what is a possible formula for M=113 (100%) on a mass spectrum? all of the above are possible molecular formulas CH130 CH15N