The image below shows the citric acid cycle. Reaction 5 is the substrate-level phosphorylation. Select the correct statement about this reaction Acetyl-CoA Condensation CH₂-C-S-CoA H₂O
The image below shows the citric acid cycle. Reaction 5 is the substrate-level phosphorylation. Select the correct statement about this reaction Acetyl-CoA Condensation CH₂-C-S-CoA H₂O
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Transcribed Image Text:Chemistry
the image below shows the citric acid cycle.
The image below shows the citric acid cycle.
Reaction 5 is the substrate-level phosphorylation. Select the correct statement about this reaction
Acetyl-CoA
Condensation
CH₂-C-S-CoA H₂O
CoA-SH
citrate
CH₂-COO™
synthase
011000
HO-C-COO™
(2a
CH₂-COO Dehydration
Dehydrogenation
Citrate
Citric acid
H₂O
aconitase
cycle
NADH
malate
Coo- dehydro-
genase
HO-CH
Malate
COO™
Hydration fumarase
H₂O
COO™
Fumarate CH
HC
coo
Dehydrogenation
CH₂
CH₂-COO
Oxaloacetate
FADH₂
succinate
dehydrogenase
CH₂-COO
CH₂
COO-
Succinate
succinyl-CoA
synthetase
Succinyl-CoA
CH-COO™
c-coo
c-c0011
aconitase
CO₂
cis-Aconitate
H₂O
(2b
Hydration
Isocitrate
Oxidative
decarboxylation
a-ketoglutarate
dehydrogenase
complex
CH₂-COO™
COA-SH
CH₂
CoA-SH
GTP
GDP C-5-CoA
(ATP)
(ADP)
+ P₁
Substrate-level
Oxidative
decarboxylation
phosphorylation
Figure 16-7
Lehninger Principles of Biochemistry, Fifth Edition
2008 W.H. Freeman and Company
O The reaction is NADH dependent
O A phosphate group is taken from the Coenzyme A substrate
O The reaction is part of 'acetyl-CoA catabolism' phase 1.
O The reaction is part of 'regeneration of oxaloacetate' phase 2.
O The reaction is a more efficient source of ATP compared to oxidative phosphorylation.
CH₂-COO™
H-C-COO™
HO-CH
isocitrate
dehydrogenase Coo
CO₂
CH₂-COO
CH₂
-a-ketoglutarate
COO™
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