Organic Chemistry of Metabolic Pathways
Metabolic pathways allude to the arrangement of chemical catalyzed reactions that lead to the transformation of a substance into the final product. Metabolic pathways incorporate a progression of reaction where the substrate is changed continuously and the transitional metabolites are persistently recovered.
Glucogenesis
Glucogenesis is a metabolic pathway in which glucose is produced from carbon substrates that are not carbohydrates. This process is observed in plants, animals, fungi, bacteria and other micro organisms. The general definition for glucogenesis or gluconeogenesis is as follows,
What happened to the Pyruvate produced during glycolysis?
Pyruvate produced after glycolysis undergoes oxidation to acquire energy as ATP. This oxidation of pyruvate in eukaryotes takes place inside the cell in mitochondria whereas in case of prokaryotes it occurs in cytoplasm.
Oxidation coverts the pyruvate into a two carbon molecule acetyl-CoA by producing NADH and CO2 as shown below.
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