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The hydrolysis of glycogen to yield glucose is catalyzed by the enzyme phosphorylase. Caffeine, which is not a carbohydrate and not a substrate for the enzyme, inhibits phosphorylase. What kind of regulatory mechanism is at work? O negative modulation O protein modification O feedback control positive modulation zymogen O isozymes

The hydrolysis of glycogen to yield glucose is catalyzed by the enzyme phosphorylase. Caffeine, which is not a carbohydrate and not a substrate for the enzyme, inhibits phosphorylase. What kind of regulatory mechanism is at work? O negative modulation O protein modification O feedback control positive modulation zymogen O isozymes

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
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### Question: The hydrolysis of glycogen to yield glucose is catalyzed by the enzyme phosphorylase. Caffeine, which is not a carbohydrate and not a substrate for the enzyme, inhibits phosphorylase. What kind of regulatory mechanism is at work? ### Options: - O negative modulation - O protein modification - O feedback control - O positive modulation - O zymogen - O isozymes ### Explanation: This question is designed to assess your understanding of different types of enzymatic regulatory mechanisms. When answering, consider the role of caffeine as an inhibitor despite not being a typical substrate for the enzyme. This situation often involves processes like competitive or non-competitive inhibition, which bears relevance to enzymatic regulation concepts.
Transcribed Image Text:### Question: The hydrolysis of glycogen to yield glucose is catalyzed by the enzyme phosphorylase. Caffeine, which is not a carbohydrate and not a substrate for the enzyme, inhibits phosphorylase. What kind of regulatory mechanism is at work? ### Options: - O negative modulation - O protein modification - O feedback control - O positive modulation - O zymogen - O isozymes ### Explanation: This question is designed to assess your understanding of different types of enzymatic regulatory mechanisms. When answering, consider the role of caffeine as an inhibitor despite not being a typical substrate for the enzyme. This situation often involves processes like competitive or non-competitive inhibition, which bears relevance to enzymatic regulation concepts.
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