Which of the following statements about G proteins is correct?O A. G proteins bind hormones.O B. G proteins bind receptor tyrosine kinases.O C. G proteins are heterodimers.O D. G proteins phosphorylate protein kinase A (PKA).O E. G proteins bind adenylate cyclaseWhich of the following steps does NOT require ATP?O A. Conversion of glucose to glucose 6-phosphateO B. Conversion of malate to pyruvateO C. Conversion of pyruvate to oxaloacetateO D. Activation of hormone sensitive lipase by PKAO E. Inactivation of glycogen synthase by PKAis an intermediate metabolite linkage between carbohydrate and fat metabolism.O A. MalateO B. OxaloacetateO C. Glucose 6-PD. Acetyl CoAO E. Malonyl COA

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Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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In Figure 4C, we see the inhibition of LRRK2 kinase activity by nanobody 1 (Nb1). Using the Lineweaver-Burke plot, estimate the Km of LRRK2 in the absence of Nb1. Show your work and provide your answer with the correct units.
Which of the following would be considered second messengers of a signaling pathway? Select one: a. A kinase enzyme b. A scaffolding protein holding three kinases c. Adenyl cyclase d. All answers are examples of second messengers e. A sugar like inositol f. Ligand gated channel
Describe the protein kinase cascade stimulated by epinephrine in liver cells or by insulin in muscle cells. How can it go wrong? What happens if it goes wrong? Explain the usefulness of protein kinase cascades and mechanisms to shut them down. Please give explanations for every step of this pathway. Define all technical terms you use.
Answer question 39
Explain Signaling by Receptors That Interact with Cytoplasmic Janus Kinases?
The fastest effect from stimulation of a G-protein-coupled receptor (GPCR) is from O CAMP G-alpha, O the shortcut pathway G-alpha G-alphas
1. EGF interacts with blank to activate the MAP kinase cascade? G protein coupled receptor; receptor Tyrosine kinase; serine/threonine kinase; cdk 2. When a trimetric G protein is activated by gpcf? The three subuni8of the G protein remain tightly associated with each other; the GDP bound to the a subunit is phosphorylated to form bound GTP; it dissociates into a free b subunit as an ay subunit; none
O Copy of Pathway divergence occurs when: O signaling pathways produce the same outcome one signaling pathway triggers another Osignaling pathways split to produce multiple outcomes. Osignaling pathways use a common intermediate Question 14 Which of the following is NOT a mechanism for halting G-protein coupled receptor signaling? receptor endocytosis. OGDP hydrolysis Arrestins 2. O ATP hydrolysis
Match each SERCA domain to its role in Ca2+ transport: Drag and drop options on the right-hand side and submit. For keyboard navigation... SHOW MORE ✓ N Domain P Domain A Domain ||| = = contains the Asp reside that can be phosphorylated Phosphatase activity Kinase Activity X X X
G proteins are involved in which 2 second messenger pathways? Pick 2 options: O The CAMP pathway the JAK-STAT pathway The calcium pathway The tyrosine kinase pathway
Which of the following are enzymes? (Select all that apply!) O Epinephrine V Actin O The Na+/K+ ATPase O Dynein O The Na+ channel O The epinephrine receptor O G-alpha O Kinesin O The lysosome O Glycogen phosphorylase O Protein kinase A O Tubulin O Glycogen O The coronavirus SARS-CoV-2
Describe the common architecture of G protein-coupled receptors. Illustrate your answer with reference to the domains that facilitate signal transduction across the plasma membrane

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Which of the following statements about G proteins is correct? O A. G proteins bind hormones. O B. G proteins bind receptor tyrosine kinases. OC. G proteins are heterodimers. O D. G proteins phosphorylate protein kinase A (PKA). O E. G proteins bind adenylate cyclase