During exercise when the body lacks an adequate supply of oxygen to support energy production, the pyruvate that is producedfrom the breakdown of glucose is converted into lactate. High lactate levels can lead to acidity in the muscle cells as some of thelactate hydrolyzes to lactic acid.The dissociation of lactic acid to lactate is shown in the reaction. Lactic acid has a pK₁ of 3.86.+ H+Love you.OHOHОНLactic acidA solution containing a mixture of lactic acid and lactate was found to have a pH of 4.11. Calculate the ratio of the lactateconcentration to the lactic acid concentration in this solution.[lactate][lactic acid]=x10TOOLSLactateУ

The dissociation of lactic acid to lactate can be represented by the following equation:Lactic acid…

Answered: The dissociation of lactic acid to…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Similar questions

Draw the amino acid below in its most protonated form, any intermediately protonated forms, and its least protonated form. Also draw a titration curve for this amino acid, with pH on the y-axis and equivalents on the x-axis going from acidic to basic (most protonated to least protonated) using the pka values below. Match the protonated/deprotonated forms to the appropriate regions of the titration curve. Scan your drawing, and upload as a pdf, jpeg, or tiff file. H3C O NH₂ pKas are provided below: OH
the following peptide is incubated as chymotrypsin: Gly-Val-Phe-Lys-Ala. Present the detailed chemical mechanism by which chymotrypsin hydrolyzes this peptide. Briefly explain each step. Include only the structure of the final products of the reaction.
Draw the (B1-->A1) linked dissacharide formed between the C3 epimer of B-D-glucose and the C2 epimer of a-D-galactose. Explain in 1-2 sentences why (or why not) a precipiate would be observed when mixing this dissacharide in an alkaline solution of copper.
The isoelectric point (pI) of 6-phosphogluconate dehydrogenase is 6.0. Explain why the buffer used in DEAE cellulose chromatography must have a pH greater than 6 but less than 9 in order for the enzyme to bind to the DEAE resin.
The structure of ephedrine isgiven, The pKa for ephedrine is 9.6. Answer the following questions about aqueous solutions of ephedrine. a. Draw the structure of the principal chemical form of ephedrine that results when it isdissolved in water.b. Draw the structure of the principal chemical form of ephedrine that results when it is dissolved in a buffer at a physiologically relevant pH of 7.4.c. Calculate the pH that results when 0.3 mole of ephedrine is dissolve in 2.0 L of 0.05 M perchloric acid (HClO4).
What is the predominant ionic form of ribose-5-phosphate at physiological pH? Would ribose-5-phosphate be a good biological buffer for cells?
Calculate the net charge of the the tripeptide Asp-Asp-Asp at pH 1.00? Please show me how to do it a. 0b. -3c. -4d. +1e. -2
Consider the proteins in the table below. Protein Isoelectric point (pl) М.W. Alcohol dehydrogenase 150,000 5.5 Cytochrome C 12,400 10.5 Serum albumin 66,000 5.3 B-Amylase 200,000 5.7 Apoferitin 443,000 4.0 Fill in the blank. If the mixture of proteins above was subjected to anion exchange chromatography at pH 8, from the column. would be the first protein to elute
A student is attempting to add asparagine to a methionine that is connected to a solid polystyrene bead. They mix together the two components below with DCC, and some of the indicated product is generated. However, more happens in this mixture, resulting in multiple products. What reactivity is happening, and how can it be avoided (to give the indicated product in high yield)?
At which pH would the peptide with the amino acid sequence 'KEYHR' be found in an IPG (Immobilized pH gradient) strip after successful isoelectric focusing. Show calculation. lonizable groups Alpha amine group of K Side chain group of K Side chain group of E Side chain group of Y Side chain group of H Side chain group of R Alpha carboxylic acid group of R pka 8.95 10.53 4.25 10.07 6 12.48 2.17
Use the two Fischer projections shown below to draw the Haworth projection of these two sugars linked by an a(1-2) linkage, with the ß isoform of the ketohexose. H H ㅎ HO H H OH OH ОН Н НО CH₂OH 애,애애 OH CH₂OH OH H OH OH OH I OH CH₂OH OH OH OH Eng са CH2OH CH2OH OH OH ОН ОН CH₂OH Н OH Н Н OH Н T I CH₂OH CH₂OH OH OH OH CH₂OH CH₂OH Н CH₂OH CH₂OH ОН OH OH НО OH H Н OH CH₂OH
The α-amylase (α-AM) enzyme secreted by Aspergillus has an isoelectric point of approximately 4.2. If the purification method in problem 1 operates at pH 6.5, would the protein carry a positive charge, negative charge, or net zero charge?

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