The anti-inflammatory agent, (S)-naproxen sodium salt has a specific rotation of +66°. The commercial preparation of the latter agent results in a mixture that has a 97% enantiomeric excess (ee). H3CO Na (S)-naproxen sodium salt (d) What percentage of each enantiomer is obtained from the above commercial mixture? (e) Provide a reaction scheme for the formation of the (S)-naproxen sodium salt from "acidic" (S)-naproxen.

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The anti-inflammatory agent, (S)-naproxen sodium salt has a specific rotation of +66°. The
commercial preparation of the latter agent results in a mixture that has a 97% enantiomeric
excess (ee).
Na
Hooooja moo
(S)-naproxen sodium salt
(d) What percentage of each enantiomer is obtained from the above commercial mixture?
H3CO
(e) Provide a reaction scheme for the formation of the (S)-naproxen sodium salt from
"acidic" (S)-naproxen.
Transcribed Image Text:The anti-inflammatory agent, (S)-naproxen sodium salt has a specific rotation of +66°. The commercial preparation of the latter agent results in a mixture that has a 97% enantiomeric excess (ee). Na Hooooja moo (S)-naproxen sodium salt (d) What percentage of each enantiomer is obtained from the above commercial mixture? H3CO (e) Provide a reaction scheme for the formation of the (S)-naproxen sodium salt from "acidic" (S)-naproxen.
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