The amino acid sequences in the lysozyme protein produced by the TF phage were studied by Streisinger and co-workers. One sequence is Lys-Ser-Pro-Ser-Leu-Asn-Ala. However, the result of a single nucleotide deletion and insertion of another nucleotide, this amino acid sequence changed to Lys-Val-His-His-Leu-Met-Ala. Using the codons in Table 13.1, determine the nucleotide sequences that produced a. the original amino acid sequence; and b. the subsequent changes.

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter28: Dna Metabolism: Replication, Recombination, And Repair
Section: Chapter Questions
Problem 16P: Helicase Unwinding of the E. coli Chromosome Hexameric helicases, such as DnaB, the MCM proteins,...
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2. The amino acid sequences in the lysozyme protein produced by the TF phage were studied by
Streisinger and co-workers. One sequence is Lys-Ser-Pro-Ser-Leu-Asn-Ala. However, the result
of a single nucleotide deletion and insertion of another nucleotide, this amino acid sequence
changed to Lys-Val-His-His-Leu-Met-Ala. Using the codons in Table 13.1, determine the nucleotide
sequences that produced
a. the original amino acid sequence; and
b. the subsequent changes.
Transcribed Image Text:2. The amino acid sequences in the lysozyme protein produced by the TF phage were studied by Streisinger and co-workers. One sequence is Lys-Ser-Pro-Ser-Leu-Asn-Ala. However, the result of a single nucleotide deletion and insertion of another nucleotide, this amino acid sequence changed to Lys-Val-His-His-Leu-Met-Ala. Using the codons in Table 13.1, determine the nucleotide sequences that produced a. the original amino acid sequence; and b. the subsequent changes.
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