The amino acid sequence shown below is a short excerpt (residues 130-172) from the rod domain of an a-keratin-like protein. Predict the effect of each of the amino acid substitutions (stabilize, destabilize, no effect) and explain your reasoning. 130 - ATEFKTRFDDAALRANDIQL VIRSNEITADLIKDRLDQITTYY - 172 a) Substitution of S in place of A at position 140. b) Substitution of V in place of I at position 147.
The amino acid sequence shown below is a short excerpt (residues 130-172) from the rod domain of an a-keratin-like protein. Predict the effect of each of the amino acid substitutions (stabilize, destabilize, no effect) and explain your reasoning. 130 - ATEFKTRFDDAALRANDIQL VIRSNEITADLIKDRLDQITTYY - 172 a) Substitution of S in place of A at position 140. b) Substitution of V in place of I at position 147.
General, Organic, and Biological Chemistry
7th Edition
ISBN:9781285853918
Author:H. Stephen Stoker
Publisher:H. Stephen Stoker
Chapter20: Proteins
Section: Chapter Questions
Problem 20.58EP: For the tripeptide SerValMet a. What amino acid is located at the peptides N-terminal end? b. What...
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![The amino acid sequence shown below is a short excerpt (residues 130-172) from the rod domain of an
a-keratin-like protein. Predict the effect of each of the amino acid substitutions (stabilize, destabilize, no effect) and
explain your reasoning.
130 - ATEFKTRFDDAALRANDIQL VIRSNEITADLIKDRLDQITTYY - 172
a) Substitution of S in place of A at position 140.
b) Substitution of V in place of I at position 147.](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F76e01451-3c62-453f-b7d8-4d01301b4a19%2Fa262b485-8f0f-4dff-9db1-6668fc56981b%2Ftirn39d_processed.png&w=3840&q=75)
Transcribed Image Text:The amino acid sequence shown below is a short excerpt (residues 130-172) from the rod domain of an
a-keratin-like protein. Predict the effect of each of the amino acid substitutions (stabilize, destabilize, no effect) and
explain your reasoning.
130 - ATEFKTRFDDAALRANDIQL VIRSNEITADLIKDRLDQITTYY - 172
a) Substitution of S in place of A at position 140.
b) Substitution of V in place of I at position 147.
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