The activity of an enzyme requires a glutamic acid to display its -COOHfunctional group in the protonated state. Suppose the pKa of the -COOHgroup is 4.07.(a) Will the enzyme be more active at pH 3.5 or 4.5? Explain.(b) What fraction of the enzymes will be active at pH = 4.07? Explain.(c) At what pH will the enzyme show 78% of maximal activity?

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