The activity of a pore-forming membrane protein, PorinA1, was tested in different lipid bilayers at 60 °C. Each bilayer is composed of a single type of phosphoglyceride. The four different phosphoglycerides used are shown in the table below together with the corresponding average hydrophobic thickness of the bilayer formed: Phosphoglyceride Bilayer hydrophobic thickness (A) Dilauroylphosphatidylcholine (DLPC) 30.7 Dimyristoylphosphatidylcholine (DMPC) 34.2 Dipalmitoylphosphatidylcholine (DPPC) 38.1 Distearoylphosphatidylcholine (DSPC) 42.2 PorinA1 is found to have the greatest activity when embedded in DPPC lipid bilayers. Which of the following values (in Á) would be the best estimate for the length of the hydrophobic region of PorinA1? O 38 O51 O 31 O 42 O 38

Biochemistry
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ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
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Chapter1: Biochemistry: An Evolving Science
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The activity of a pore-forming membrane protein, PorinA1, was tested in different lipid bilayers at 60 °C. Each bilayer is composed of a single type of phosphoglyceride. The four different phosphoglycerides used
are shown in the table below together with the corresponding average hydrophobic thickness of the bilayer formed:
Phosphoglyceride
Bilayer hydrophobic thickness ( A)
Dilauroylphosphatidylcholine (DLPC)
30.7
Dimyristoylphosphatidylcholine (DMPC)
34.2
Dipalmitoylphosphatidylcholine (DPPC)
38.1
Distearoylphosphatidylcholine (DSPC)
42.2
PorinA1 is found to have the greatest activity when embedded in DPPC lipid bilayers. Which of the following values (in A) would be the best estimate for the length of the hydrophobic region of PorinA1?
O 38
O 51
O 31
O 42
O 38
Transcribed Image Text:The activity of a pore-forming membrane protein, PorinA1, was tested in different lipid bilayers at 60 °C. Each bilayer is composed of a single type of phosphoglyceride. The four different phosphoglycerides used are shown in the table below together with the corresponding average hydrophobic thickness of the bilayer formed: Phosphoglyceride Bilayer hydrophobic thickness ( A) Dilauroylphosphatidylcholine (DLPC) 30.7 Dimyristoylphosphatidylcholine (DMPC) 34.2 Dipalmitoylphosphatidylcholine (DPPC) 38.1 Distearoylphosphatidylcholine (DSPC) 42.2 PorinA1 is found to have the greatest activity when embedded in DPPC lipid bilayers. Which of the following values (in A) would be the best estimate for the length of the hydrophobic region of PorinA1? O 38 O 51 O 31 O 42 O 38
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