The ability to calculate moles/millimoles, equivalents of reagents, expected product yield, and actual yield is imperative for this lab course (The properties of most sm and reagents can be found at! ..) Answer Q1-Q4 with respect to the Grignard reaction below, and remember to show all calculations with units and all amounts in g/mg or mL depending on the chemical's properties: Br OH i) Mg (1.3 equiv.), Et₂O Me ii) n-PrCHO (1.3 equiv.) 1 equiv. Q1) As bromobenzene is a liquid, the specific volume needed is calculated in mL for delivery via syringe. (Only when either using a highly viscous liquid or when running on an extremely large multi-kg scale is a liquid weighed on a balance.) How many mL of bromobenzene (PhBr) are needed on a 0.0256 mol scale (as 1 equiv. means that BnBr is the limiting reagent)? Q2) Q3) Q4) On the same Q1 reaction scale, how much magnesium (Mg) metal is needed? On the same Q1 reaction scale, how much butyraldehyde (n-PrCHO) is needed? On the same Q1 reaction scale, calculate the theoretical yield (mass) of product. Grignard reagents can be prepared in advance, titrated, and stored. Many of the most commonly used Grignards can be purchased with advertised molarities (M). Given a different experimental procedure requiring 0.95 equivalents of PhMgCl (2.0 M in THF) and 1.0 equivalents of butyraldehyde, what amounts of each are needed on 14.5 mmol scale?

EBK A SMALL SCALE APPROACH TO ORGANIC L
4th Edition
ISBN:9781305446021
Author:Lampman
Publisher:Lampman
Chapter20: Nucleophilic Substitution Reactions: Competing Nucleophiles
Section: Chapter Questions
Problem 8Q
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The ability to calculate moles/millimoles, equivalents of reagents, expected product yield, and
actual yield is imperative for this lab course (The properties of most sm and reagents can be found
at!
..) Answer Q1-Q4 with respect to the Grignard reaction
below, and remember to show all calculations with units and all amounts in g/mg or mL depending
on the chemical's properties:
Br
OH
i) Mg (1.3 equiv.), Et₂O
Me
ii) n-PrCHO (1.3 equiv.)
1 equiv.
Q1) As bromobenzene is a liquid, the specific volume needed is calculated in mL for delivery
via syringe. (Only when either using a highly viscous liquid or when running on an extremely
large multi-kg scale is a liquid weighed on a balance.) How many mL of bromobenzene (PhBr)
are needed on a 0.0256 mol scale (as 1 equiv. means that BnBr is the limiting reagent)?
Q2)
Q3)
Q4)
On the same Q1 reaction scale, how much magnesium (Mg) metal is needed?
On the same Q1 reaction scale, how much butyraldehyde (n-PrCHO) is needed?
On the same Q1 reaction scale, calculate the theoretical yield (mass) of product.
Grignard reagents can be prepared in advance, titrated, and stored. Many of the most
commonly used Grignards can be purchased with advertised molarities (M).
Given a different experimental procedure requiring 0.95 equivalents of PhMgCl (2.0 M in THF)
and 1.0 equivalents of butyraldehyde, what amounts of each are needed on 14.5 mmol scale?
Transcribed Image Text:The ability to calculate moles/millimoles, equivalents of reagents, expected product yield, and actual yield is imperative for this lab course (The properties of most sm and reagents can be found at! ..) Answer Q1-Q4 with respect to the Grignard reaction below, and remember to show all calculations with units and all amounts in g/mg or mL depending on the chemical's properties: Br OH i) Mg (1.3 equiv.), Et₂O Me ii) n-PrCHO (1.3 equiv.) 1 equiv. Q1) As bromobenzene is a liquid, the specific volume needed is calculated in mL for delivery via syringe. (Only when either using a highly viscous liquid or when running on an extremely large multi-kg scale is a liquid weighed on a balance.) How many mL of bromobenzene (PhBr) are needed on a 0.0256 mol scale (as 1 equiv. means that BnBr is the limiting reagent)? Q2) Q3) Q4) On the same Q1 reaction scale, how much magnesium (Mg) metal is needed? On the same Q1 reaction scale, how much butyraldehyde (n-PrCHO) is needed? On the same Q1 reaction scale, calculate the theoretical yield (mass) of product. Grignard reagents can be prepared in advance, titrated, and stored. Many of the most commonly used Grignards can be purchased with advertised molarities (M). Given a different experimental procedure requiring 0.95 equivalents of PhMgCl (2.0 M in THF) and 1.0 equivalents of butyraldehyde, what amounts of each are needed on 14.5 mmol scale?
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