3. Diazepam tablets are supplied in 2-, 5-, and 10-mg increments. Suppose several tablets are received in a laboratory as evidence and using the Physician's Desk Reference, an analyst can tentatively identify them as Valium, 10mg. Suppose further that you learn that the tablets also contain anhydrous lactose, starches, dyes, and calcium stearate. Describe a method for isolating the active ingredient from fillers, using an LLE scheme. Justify and explain each step of the method. 4. Quinine (C20 H24N2O2) is a dibasic molecule with pKa's of 5.07 and 9.7. It is encountered as a diluent (cutting agent) for heroin. To extract quinine from an aqueous solution, what pH should be used and why?

3. Diazepam tablets are supplied in 2-, 5-, and 10-mg increments. Suppose several tablets are received in a laboratory as evidence and using the Physician's Desk Reference, an analyst can tentatively identify them as Valium, 10mg. Suppose further that you learn that the tablets also contain anhydrous lactose, starches, dyes, and calcium stearate. Describe a method for isolating the active ingredient from fillers, using an LLE scheme. Justify and explain each step of the method. 4. Quinine (C20 H24N2O2) is a dibasic molecule with pKa's of 5.07 and 9.7. It is encountered as a diluent (cutting agent) for heroin. To extract quinine from an aqueous solution, what pH should be used and why?

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter23: Amines

Section: Chapter Questions

Problem 23.26P: The pKa, of the conjugate acid of morpholine is 8.33. (a) Calculate the ratio of morpholine to...

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