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strain of Moraxella catarrhalis is able to grow on agar containing the antibiotic amoxicillin. You uspect this strain may contain the enzyme B-lactamase which inactivates amoxicillin, making it neffective as an antibiotic. You grow the same strain in media containing amoxicillin and clavulanic cid (a B-lactamase inhibitor). What do expect the results to be; growth or no growth? Explain.

strain of Moraxella catarrhalis is able to grow on agar containing the antibiotic amoxicillin. You uspect this strain may contain the enzyme B-lactamase which inactivates amoxicillin, making it neffective as an antibiotic. You grow the same strain in media containing amoxicillin and clavulanic cid (a B-lactamase inhibitor). What do expect the results to be; growth or no growth? Explain.

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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**Transcription for Educational Website** --- ### Microbiology: Selective Media and Antibiotic Resistance **Selective Media:** Phenylethyl alcohol agar is a type of selective media. It is used to permit the growth of gram-positive bacteria while inhibiting the growth of gram-negative bacteria. **Discussion on β-lactamase Enzyme and Antibiotic Resistance:** A strain of *Moraxella catarrhalis* is observed to grow on agar containing the antibiotic amoxicillin. This suggests that the strain may produce the enzyme β-lactamase, which inactivates amoxicillin, rendering it ineffective as an antibiotic. **Experimental Approach:** To confirm this, the same strain is grown in media containing both amoxicillin and clavulanic acid, a β-lactamase inhibitor. **Expected Results:** - **Growth:** If the strain still grows, it indicates that clavulanic acid is unable to inhibit the β-lactamase enzyme effectively. - **No Growth:** If there is no growth, clavulanic acid successfully inhibits the β-lactamase enzyme, allowing amoxicillin to remain effective. This experiment helps in understanding antibiotic resistance mechanisms and the role of enzyme inhibitors in overcoming resistance. --- No graphs or diagrams were present in the text provided.
Transcribed Image Text:**Transcription for Educational Website** --- ### Microbiology: Selective Media and Antibiotic Resistance **Selective Media:** Phenylethyl alcohol agar is a type of selective media. It is used to permit the growth of gram-positive bacteria while inhibiting the growth of gram-negative bacteria. **Discussion on β-lactamase Enzyme and Antibiotic Resistance:** A strain of *Moraxella catarrhalis* is observed to grow on agar containing the antibiotic amoxicillin. This suggests that the strain may produce the enzyme β-lactamase, which inactivates amoxicillin, rendering it ineffective as an antibiotic. **Experimental Approach:** To confirm this, the same strain is grown in media containing both amoxicillin and clavulanic acid, a β-lactamase inhibitor. **Expected Results:** - **Growth:** If the strain still grows, it indicates that clavulanic acid is unable to inhibit the β-lactamase enzyme effectively. - **No Growth:** If there is no growth, clavulanic acid successfully inhibits the β-lactamase enzyme, allowing amoxicillin to remain effective. This experiment helps in understanding antibiotic resistance mechanisms and the role of enzyme inhibitors in overcoming resistance. --- No graphs or diagrams were present in the text provided.
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