SN2 reactions takes place with inversion of configuration, while SN1 reaction takes place with racemization. The following substitution reaction however, occurs with complete retention of configuration. Propose a mechanism. CH, CH, но 1. 1% NAOH, H,0 он Br HO 2. Н,о

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Q: 6. Show the mechanism for the following reaction. MeO Br BF3 MeO

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Reactions at the Alpha Carbon Atom

The position next to the ketone or aldehyde functional group is termed as alpha position and the reaction which occurs at alpha position is called alpha substitution reaction. In an alpha substitution reaction, the alpha proton atom is substituted by an electrophile by the formation of an enol intermediate or enolate ion intermediate. Most of the carbonyl compounds go through an alpha substitution reaction.