Imines are electrophiles in the related Mannich reaction. Draw two transition states, one leading to the syn diastereomer and one leading to the anti. Briefly explain which is favoured and why. Assume the imine doesn't change geometry.
Imines are electrophiles in the related Mannich reaction. Draw two transition states, one leading to the syn diastereomer and one leading to the anti. Briefly explain which is favoured and why. Assume the imine doesn't change geometry.
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Transcribed Image Text:Imines are electrophiles in the related Mannich reaction. Draw two transition states, one leading to the syn
diastereomer and one leading to the anti. Briefly explain which is favoured and why. Assume the imine doesn't
change geometry.
OM
H3G
CH3
Ph
CH3
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