Imines are electrophiles in the related Mannich reaction. Draw two transition states, one leading to the syn diastereomer and one leading to the anti. Briefly explain which is favoured and why. Assume the imine doesn't change geometry.

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Imines are electrophiles in the related Mannich reaction. Draw two transition states, one leading to the syn
diastereomer and one leading to the anti. Briefly explain which is favoured and why. Assume the imine doesn't
change geometry.
OM
H3G
CH3
Ph
CH3
Transcribed Image Text:Imines are electrophiles in the related Mannich reaction. Draw two transition states, one leading to the syn diastereomer and one leading to the anti. Briefly explain which is favoured and why. Assume the imine doesn't change geometry. OM H3G CH3 Ph CH3
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