Side effects Even if an experiment is double-blind, the blinding might be compromised if side effects of the treatments differ. For example, suppose researchers at a skin-care company are comparing their new acne treatment against the leading competitor. Fifty subjects are assigned at random to each treatment, and the company's researchers will rate the improvement for each of the 100 subjects. The researchers aren't told which subjects received which treatments, but they know that their new acne treatment causes a slight reddening of the skin. How might this knowledge compromise the blinding? Explain why this is an important consideration in this experiment.

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12.
Side effects Even if an experiment is double-blind, the blinding might be
compromised if side effects of the treatments differ. For example, suppose
researchers at a skin-care company are comparing their new acne
treatment against the leading competitor. Fifty subjects are assigned at
random to each treatment, and the company's researchers will rate the
improvement for each of the 100 subjects. The researchers aren't told
which subjects received which treatments, but they know that their new
acne treatment causes a slight reddening of the skin. How might this
knowledge compromise the blinding? Explain why this is an important
consideration in this experiment.
Transcribed Image Text:12. Side effects Even if an experiment is double-blind, the blinding might be compromised if side effects of the treatments differ. For example, suppose researchers at a skin-care company are comparing their new acne treatment against the leading competitor. Fifty subjects are assigned at random to each treatment, and the company's researchers will rate the improvement for each of the 100 subjects. The researchers aren't told which subjects received which treatments, but they know that their new acne treatment causes a slight reddening of the skin. How might this knowledge compromise the blinding? Explain why this is an important consideration in this experiment.
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