Semicarbazones Carbonyl compounds Mix 1 mL of the semi carbazide hydrochloride with 40 mg of the unknown. Add 1mL of methanol to make the solution clear. Add 15 drops of pyridine and warm on a water bath for 5 min. Cool to room temperature, put in ice, and scratch to induce crystallization. Collect the product by suction filtration and wash with cold water. Recrystallize from methanol, ethanol, or ethanol-water mixture and let it dry until next time. 2,4 Dinitrophenylhydrazones Mix 2.5 mL of 2,4-dinitrophenylhydrazine in phosphoric acid and 25 mg of the unknown. Warm in a water bath for 5 min and let crystallization proceed. Collect the product by suction filtration and wash the crystals with cold water. Recrystallize from ethanol and let it dry until next time. NHÁNH, Re N-NH- -NO₂ + R✗ R' O₂N NO₂ R' O₂N Re NH₂ H₂N N-NH2 R'

Semicarbazones Carbonyl compounds Mix 1 mL of the semi carbazide hydrochloride with 40 mg of the unknown. Add 1mL of methanol to make the solution clear. Add 15 drops of pyridine and warm on a water bath for 5 min. Cool to room temperature, put in ice, and scratch to induce crystallization. Collect the product by suction filtration and wash with cold water. Recrystallize from methanol, ethanol, or ethanol-water mixture and let it dry until next time. 2,4 Dinitrophenylhydrazones Mix 2.5 mL of 2,4-dinitrophenylhydrazine in phosphoric acid and 25 mg of the unknown. Warm in a water bath for 5 min and let crystallization proceed. Collect the product by suction filtration and wash the crystals with cold water. Recrystallize from ethanol and let it dry until next time. NHÁNH, Re N-NH- -NO₂ + R✗ R' O₂N NO₂ R' O₂N Re NH₂ H₂N N-NH2 R'

Macroscale and Microscale Organic Experiments

7th Edition

ISBN:9781305577190

Author:Kenneth L. Williamson, Katherine M. Masters

Publisher:Kenneth L. Williamson, Katherine M. Masters

Chapter4: Recrystallization

Section: Chapter Questions

Problem 1Q

See similar textbooks

Similar questions

Compound Phthalic Acid *Formula: C ₂ H 6 Ou Naphthalene Water Methanol Structure +01 with purity Pu ON Mol (g/m Procedure: 1. Prepare Hot Water for Recrystallizations 16 ( 12 All data and observation taken during lab should with a single line so the original is still legible. Add-100 mL of water to a 125-mL Erlenme Add a boiling stone to prevent bumping dur
What method of separation would you use to isolate compound B from an ether solution containing a mixture of the two compounds below? OH A B Extract with base, isolate the aqueous layer, neutralize with acid, filter the precipitate and dry Extract with acid, isolate the aqueous layer, neutralize with base, filter the precipitate and dry Extract with base, isolate the organic layer, dry with magnesium sulfate, and evaporate the solvent Extract with acid, isolate the organic layer, dry with magnesium sulfate, and evaporate the solvent Extract with base, isolate the organic layer, neutralize with acid, filter the precipitate and dry Extract with acid, isolate the organic layer, neutralize with base, filter the precipitate and dry
1. Describe the preparation of 500mL of 0.500M KMNO4 from the solid reagent. 2.Describe the preparation of 500mL of 4.75% (W/V) aqueous ethanol (C2H5OH, 46.1g/mol).
2.1g of sample are dissolved in methylene chloride and the sample is extracted with aqueous solutions of acid and base. Three compounds are isolated - 0.8g of ethyl p-aminobenzoate, 0.6 g of acetanilide, and 0.5 g of benzoic acid. Calculate the % recovery for the procedure. (Round the answer to the nearest tens place.) Give just the number, not a % sign.)
TRUE OR FALSE, if false then give the correct word to make the statement true then explain 1. Sublimation occurs when a solid has a relatively high vapor pressure at a temperature [above] its melting point. 2. To isolate the desired chemical, a single extraction is [more efficient] than extracting the compound numerous times. 3. The compounds are separated in liquid-liquid extraction based on their relative solubilities in two [immiscible] liquids.
How to prepare, 0.8 N of MgS04 (Mol. wt. 104 and the charge is 2) in 0.5 L. Dissolve 20.8 grams of MgSO4 in 500 ml of H2O. Dissolve 41.6 grams of MgS04 in 0.5L of H2O. Dissolve 27 grams of MgSO4 in 0.5L of H2o. Dissolve 18 grams of MgSO4 in 0.5L of H2O. A Moving to the next question prevents changes to this answer.
When isolating the solid after recrystallization using vacuum filtration what solvent should you use to aid in the rinse from the Erlenmeyer flask to the vacuum filter funnel? (Only pick one answer) Group of answer choices: Cold ethyl acetate Cold ethanol Hot ethyl acetate Hot ethanol Hot water Cold water None of the above, it should not be risned
Which of the following mixtures can be efficiently separated by simple distillation? a.) H2ONACI B.) CH3OH / H20 C.) CH3CH2CH2CH2CH2CH3 and CH3CH2CH2CH2CH3 D.) CH3COCH3 (acetone) and CH3CH20CH2CH3 (diethyl ether)
During your first day on the job as a research assistant, you are preparing 50 mL of hybridization solution with the following components and working concentrations: 50% formamide 5X sodium salt citrate 0.5% sodium dodecyl sulfate You start from the following concentrated stock solutions: 100% formamide 20X sodium salt citrate 20% sodium dodecyl sulfate How much of each concentrated stock solution and water will you add?
Which of the following would LOWER the purity of the distillate collected from the rubbing alcohol mixture? Using cold water in the condenserII. Not discarding the first milliliter distilledIII. Addition of boiling chips into the mixtureIV. Maintaining the temperature of the hot plate above 100°C Select one: I and II III and IV II and IV II only
19. A liquefied mixture of n-butane, n-pentane, and n-hexane has the following composition: n-C,H10 50%, n-C,H12 30%, and n-C,H14 20%. For this mixture, calculate: a) The weight fraction of each component. b) The mole fraction of each component. c) The mole percent of each component. d) The average molecular weight of the mixture.
Reagent Table: Reagent pro Molar equilaments Sabicbeade/M.W. (Mammal equilaments Salcylamide 137.1 mg/mmol 1.0 Sodium Iodide (val) 149.9 mg/mmol 1.15 Sodium Hypochlorite 57% 74.44mg/mmol (Nara) 951 Ethanol NW Solvent mmoles Immotes 14.6mm 16-79mmol Weight grams or VLCm 29 2.52g 1.207: 17.52mmol 17.52 mmol 22.88mL 40m² A Ль A