Saccharide Y is a tetrasaccharide. To determine its linkages, glycopeptide X was exhaustively methylated, effectively methylating saccharide Y. Cleavage gave a polypeptide and the following products: 2,3,4-tri-O-methyl-a-D-glucopyranoside acid, 2,3- di-O-methyl-ß-D-glucopyranoside, 1,3,4-tri-O-methyl-ß-D-glucuronic acid and 1,4,6-tri-O- methyl-ß-D-N-acetylgalactosamine. Further treatments to the isolated tetrasaccharide gave the following results: A. Treatment of saccharide Y with an a-1,4 glycosidase gave a trisaccharide and glucopyranose B. Treatment of saccharide Y with a 2,6-glycosidase also gave a trisaccharide and glucuronic acid. Draw the structure of the saccharide.
Saccharide Y is a tetrasaccharide. To determine its linkages, glycopeptide X was exhaustively methylated, effectively methylating saccharide Y. Cleavage gave a polypeptide and the following products: 2,3,4-tri-O-methyl-a-D-glucopyranoside acid, 2,3- di-O-methyl-ß-D-glucopyranoside, 1,3,4-tri-O-methyl-ß-D-glucuronic acid and 1,4,6-tri-O- methyl-ß-D-N-acetylgalactosamine. Further treatments to the isolated tetrasaccharide gave the following results: A. Treatment of saccharide Y with an a-1,4 glycosidase gave a trisaccharide and glucopyranose B. Treatment of saccharide Y with a 2,6-glycosidase also gave a trisaccharide and glucuronic acid. Draw the structure of the saccharide.
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
Related questions
Question
Transcribed Image Text:Saccharide Y is a tetrasaccharide. To determine its linkages, glycopeptide X was
exhaustively methylated, effectively methylating saccharide Y. Cleavage gave a
polypeptide and the following products: 2,3,4-tri-O-methyl-a-D-glucopyranoside acid, 2,3-
di-O-methyl-ß-D-glucopyranoside, 1,3,4-tri-O-methyl-ß-D-glucuronic acid and 1,4,6-tri-O-
methyl-ß-D-N-acetylgalactosamine. Further treatments to the isolated tetrasaccharide
gave the following results:
A. Treatment of saccharide Y with an a-1,4 glycosidase gave a trisaccharide and
glucopyranose
B. Treatment of saccharide Y with a 2,6-glycosidase also gave a trisaccharide and
glucuronic acid.
Draw the structure of the saccharide.
Expert Solution
This question has been solved!
Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.
Step by step
Solved in 2 steps with 2 images
Recommended textbooks for you
Biochemistry
Biochemistry
ISBN:
9781319114671
Author:
Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:
W. H. Freeman
Lehninger Principles of Biochemistry
Biochemistry
ISBN:
9781464126116
Author:
David L. Nelson, Michael M. Cox
Publisher:
W. H. Freeman
Fundamentals of Biochemistry: Life at the Molecul…
Biochemistry
ISBN:
9781118918401
Author:
Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher:
WILEY
Biochemistry
Biochemistry
ISBN:
9781319114671
Author:
Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:
W. H. Freeman
Lehninger Principles of Biochemistry
Biochemistry
ISBN:
9781464126116
Author:
David L. Nelson, Michael M. Cox
Publisher:
W. H. Freeman
Fundamentals of Biochemistry: Life at the Molecul…
Biochemistry
ISBN:
9781118918401
Author:
Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher:
WILEY
Biochemistry
Biochemistry
ISBN:
9781305961135
Author:
Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher:
Cengage Learning
Biochemistry
Biochemistry
ISBN:
9781305577206
Author:
Reginald H. Garrett, Charles M. Grisham
Publisher:
Cengage Learning
Fundamentals of General, Organic, and Biological …
Biochemistry
ISBN:
9780134015187
Author:
John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. Peterson
Publisher:
PEARSON