52.17 There is another melanocyte-stimulating hormone called ß-melanotropin. Cleavage of B-melanotropin with trypsin produces the following peptides plus free aspartic acid.WGSPPK, DSGPYK, MEHFRPart AIf you assume maximum sequence similarity between a-melanotropin and B-melanotropin, then what must the sequence of the latter be?(a -melanotropin: Ser- Tyr- Ser- Met- Glu- His- Phe- Arg- Trp- Gly- Lys- Pro- Val)Drag the appropriate labels to their respective targets so that the maximum sequence similarity to the order of a-melanotropin will be shown.MEHFRWGSPPKDSGPYKResetHelp

There is another melanocyte-stimulating hormone called B-melanotropin. Cleavage of 3-melanotropin with trypsin produces the following peptides plus free aspartic acid. WGSPPK, DSGPYK, MEHFR Part A If you assume maximum sequence similarity between a-melanotropin and 3-melanotropin, then what must the sequence of the latter be? (a -melanotropin: Ser- Tyr- Ser-Met- Glu- His- Phe- Arg- Trp- Gly- Lys- Pro- Val) Drag the appropriate labels to their respective targets so that the maximum sequence similarity to the order of a-melanotropin will be shown. MEHFR WGSPPK DSGPYK Reset Help

There is another melanocyte-stimulating hormone called B-melanotropin. Cleavage of 3-melanotropin with trypsin produces the following peptides plus free aspartic acid. WGSPPK, DSGPYK, MEHFR Part A If you assume maximum sequence similarity between a-melanotropin and 3-melanotropin, then what must the sequence of the latter be? (a -melanotropin: Ser- Tyr- Ser-Met- Glu- His- Phe- Arg- Trp- Gly- Lys- Pro- Val) Drag the appropriate labels to their respective targets so that the maximum sequence similarity to the order of a-melanotropin will be shown. MEHFR WGSPPK DSGPYK Reset Help

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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92.17
2.7 Now that you have figured out the reaction mechanism, let's explore the action mechanism of the following drug. Notice that this molecule is composed of two chloroethylamine groups and therefore can react with two different nucleophiles. Complete the following reaction mechanism. R-N Cl CL + R'-NH₂ R"-NH₂ The above reaction is responsible for the activity of the drug. Because of its ability to react with two nucleophiles, the drug can create a bridge between two biologically active molecules and disrupt their activity. This process is known as 'cross-linking'. For example, it can react with two DNA strands and prevent their separation during replication. This will cause cytotoxicity and cell death. 2.8 Draw a scheme/cartoon to represent the general idea of chemical cross-linking described above.
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20-92 How many different primary structures are possible for a four-amino-acid segment of a protein if three of the amino acids present must be identical the four amino acids must be different
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